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Identification of p...
Identification of potentially toxic compounds in complex extracts of environmental samples using gas chromatography-mass spectrometry and multivariate data analysis
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Bergknut, Magnus (author)
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Kucera, Adam (author)
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Frech, Kristina (author)
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- Andersson, Erika (author)
- Örebro universitet,Institutionen för naturvetenskap,Bioanalytisk miljötoxikologi
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- Engwall, Magnus (author)
- Örebro universitet,Institutionen för naturvetenskap,Bioanalytisk miljötoxikologi
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- Rannug, Ulf (author)
- Stockholms universitet,Institutionen för genetik, mikrobiologi och toxikologi
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Koci, Vladimir (author)
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Andersson, Patrik L. (author)
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Haglund, Peter (author)
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Tysklind, Mats (author)
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(creator_code:org_t)
- New York : Pergamon, 2007
- 2007
- English.
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In: Environmental Toxicology and Chemistry. - New York : Pergamon. - 0730-7268 .- 1552-8618. ; 26:2, s. 208-217
- Related links:
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http://www.ncbi.nlm....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- In this study, we examined 31 samples of varying chemical composition, including samples of soils from gasworks, coke production sites, and sites where wood preservatives were heavily used; ash and soot from municipal solid waste incinerators; antiskid sand; and dust from areas with heavy road traffic. The samples were comprehensively chemically characterized, especially their polycyclic aromatic compound contents, using gas chromatography-time-of-flight mass spectrometry, whereas their biological effects were assessed using dehydrogenase activity, root growth (Hordeum vulgare), reproduction of springtails (Folsomia candida), algal growth (Desmodesmus subspicatus), germinability (Sinapis alba), Vibrio fischeri, DR-CALUX, and Ames Salmonella assays. The number of compounds detected in the samples ranged from 123 to 527. Using the multivariate regression technique of partial-least-squares projections to latent structures, it was possible to find individual compounds that exhibited strong correlations with the different biological responses. Some of the results, however, indicate that a broader chemical characterization may be needed to identify all the compounds that may cause the measured biological responses.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- Environmental Pollutants/*toxicity
- Gas Chromatography-Mass Spectrometry/*methods
- Multivariate Analysis
- Environmental toxicology
- Miljötoxikologi
- NATURAL SCIENCES
- NATURVETENSKAP
- Environmental chemistry
- Miljökemi
- Miljökemi
- Environmental Chemistry
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Bergknut, Magnus
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Kucera, Adam
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Frech, Kristina
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Andersson, Erika
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Engwall, Magnus
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Rannug, Ulf
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show more...
-
Koci, Vladimir
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Andersson, Patri ...
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Haglund, Peter
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Tysklind, Mats
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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and Environmental Sc ...
- Articles in the publication
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Environmental To ...
- By the university
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Örebro University
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Stockholm University