Search: onr:"swepub:oai:DiVA.org:oru-49514" >
The expression of E...
The expression of EGFR family ligands in breast carcinomas
-
- Suo, Zhenhe (author)
- Departments of Pathology, The Norwegian Radium Hospital and Institute for Cancer Research, University of Oslo, Oslo, Norway
-
- Risberg, Bjørn (author)
- Departments of Pathology, The Norwegian Radium Hospital and Institute for Cancer Research, University of Oslo, Oslo, Norway
-
- Karlsson, Mats G, 1960- (author)
- Department of Pathology, Örebro Medical Center Hospital, Örebro, Sweden
-
show more...
-
- Villman, Kenneth (author)
- Department of Oncology, Örebro Medical Center Hospital, Örebro, Sweden
-
- Skovlund, Eva (author)
- Department of Clinical Research, The Norwegian Radium Hospital and Institute for Cancer Research, University of Oslo, Oslo, Norway
-
- Nesland, Jahn M. (author)
- Departments of Pathology, The Norwegian Radium Hospital and Institute for Cancer Research, University of Oslo, Oslo, Norway
-
show less...
-
(creator_code:org_t)
- 2016-07-27
- 2002
- English.
-
In: International Journal of Surgical Pathology. - Thousand Oaks, USA : Sage Publications. - 1066-8969 .- 1940-2465. ; 10:2, s. 91-99
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Expression of EGF, HB-EGF, TGF-alpha, HRG-alpha, HRG-beta1, and HRG-beta3 in 100 frozen breast carcinoma materials was immunohistochemically studied. Among these tumors, 67% were positive for EGF, 53% for HB-EGF, 57% for TGF-alpha, 60% for HRG-alpha, 53% for HRG-beta1, and 63% for HRG-beta3 in the neoplastic epithelial cells. No significant associations between expression of the growth factors and clinicopathological features like tumor size, histologic grade, node status, ploidy, ER status, and c-erbB-4 expression were observed, with the exceptions that significant relations were present between EGF expression and tumor size (p = 0.01) and between HRG-beta3 expression and node status (p = 0.02). The expressions of these growth factors showed no association with cancer-specific survival by the Kaplan Meier analysis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database