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Differences in CD14...
Differences in CD14 and alpha-naphthyl acetate esterase positivity and relation to prognosis in AML
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- Fergedal, May (author)
- Department of Pathology, Örebro Medical Center Hospital, Örebro, Sweden
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- Åström, Maria, 1959- (author)
- Department of Internal Medicine, Örebro Medical Center Hospital, Örebro, Sweden
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- Tidefelt, Ulf, 1951- (author)
- Department of Internal Medicine, Örebro Medical Center Hospital, Örebro, Sweden
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- Karlsson, Mats G., 1960- (author)
- Department of Pathology, Örebro Medical Center Hospital, Örebro, Sweden
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(creator_code:org_t)
- Oxford, United Kingdom : Elsevier, 1998
- 1998
- English.
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In: Leukemia Research. - Oxford, United Kingdom : Elsevier. - 0145-2126 .- 1873-5835. ; 22:1, s. 25-30
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Alpha-naphthyl acetate esterase (ANAE) and CD14 expression, used for determination of monocytic cells, were compared and related to prognosis in 65 AML patients. Bone marrow aspiration material from AML patients has been used for the cytochemistry as well as flow cytometry. All non-erythroid cells have been included in the evaluation in both methods. 17/65 cases showed at least 15% difference between the proportion CD14 and ANAE positive cells. Cases with 20% or more CD14 positivity had poorer prognosis. For FAB classes M0-M3, presence of 10% or more CD14 was negative for overall survival (P = 0.01). ANAE did not show significant prognostic influence.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Keyword
- CD14
- esterase
- acute non-lymphocytic leukemia
- prognosis
Publication and Content Type
- ref (subject category)
- art (subject category)
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