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Graft patency is as...
Graft patency is associated with higher health-related quality of life after coronary artery bypass surgery
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- Samano, Ninos, 1972- (author)
- Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper,Department of Cardiothoracic and Vascular Surgery, Örebro University Hospital, Örebro, Sweden
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- Bodin, Lennart, 1941- (author)
- Karolinska Institutet
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- Karlsson, Jan, 1950- (author)
- Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper,University Health Care Research Center, Region Örebro County, Örebro, Sweden
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- Geijer, Håkan, 1961- (author)
- Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper,Department of Radiology, Örebro University Hospital, Örebro, Sweden
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- Arbeus, Mikael (author)
- Department of Cardiothoracic and Vascular Surgery, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden
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- Souza, Domingos (author)
- Region Örebro län,Department of Cardiothoracic and Vascular Surgery, Örebro University Hospital, Örebro, Sweden
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(creator_code:org_t)
- 2016-12-31
- 2016
- English.
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In: Interactive Cardiovascular and Thoracic Surgery. - Oxford, USA : Oxford University Press. - 1569-9293 .- 1569-9285. ; 24:3, s. 388-394
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Abstract
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- Objectives: The objective of this study was to investigate whether graft patency was associated with higher health-related quality of life in coronary artery bypass grafting patients and to compare this study with the general Swedish population.Methods: Patients were included from 3 randomized trials and 1 prospective cohort trial. The generic health-related quality of life instrument, EQ-5D (VAS and index) was used. Graft patency was assessed with computed tomography angiography. Patients were divided into 2 groups according to the number of occluded distal anastomosis: Group I with no to 1 occlusion (n = 209) and Group II with 2 to 4 occlusions (n = 24).Results: Two hundred and thirty-three patients underwent computed tomography angiography at a mean of 7.5 (1-18) years post-operatively. The mean difference in EQ-VAS and EQ-5D index between Groups II and I after model adjustment was -19.8 (95% CI -25.3 to -14.3; P < 0.001) and -0.13 (95% CI -0.19 to -0.08; P < 0.001), respectively. The EQ-5D index for the study population was similar compared with the Swedish population, 0.851 and 0.832, respectively, with an effect-size of 0.112 (trivial). The EQ-5D index of the study population was higher compared with the ischemic heart disease group in the Swedish population, 0.851 vs 0.60, with an effect-size of 0.999 (large).Conclusion: Graft patency was associated with higher health-related quality of life in coronary artery bypass patients. This patient group reported similar function and wellbeing compared to the general Swedish population and better health status than those in the same disease group in the general population.Clinical registration number: Clinicaltrials.gov: NCT02547194 and the Research and Development registry in Sweden: 167861.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Coronary artery bypass grafting
- EQ-5D
- health-related quality of life
- left internal thoracic artery
- no-touch saphenous
- Cardiology
- Kardiologi
- Kirurgi
- Surgery
Publication and Content Type
- ref (subject category)
- art (subject category)
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Samano, Ninos, 1 ...
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Bodin, Lennart, ...
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Karlsson, Jan, 1 ...
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Geijer, Håkan, 1 ...
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Arbeus, Mikael
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Souza, Domingos
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
- Articles in the publication
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Interactive Card ...
- By the university
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Örebro University
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Karolinska Institutet