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Genetic innovation ...
Genetic innovation and stability in externalizing problem behavior across development : a multi-informant twin study
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- Wichers, M. (author)
- Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network (EURON), Maastricht University, Maastricht, The Netherlands
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- Gardner, C. (author)
- Virginia Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA; Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA
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- Maes, H. H. (author)
- Virginia Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA; Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA
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- Lichtenstein, P. (author)
- Karolinska Institutet
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- Larsson, Henrik, 1975- (author)
- Karolinska Institutet
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- Kendler, K. S. (author)
- Virginia Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA; Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA; Department of Human and Molecular Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond VA, USA
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(creator_code:org_t)
- 2013-02-03
- 2013
- English.
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In: Behavior Genetics. - New York, USA : Springer. - 0001-8244 .- 1573-3297. ; 43:3, s. 191-201
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- The use of cross-informant ratings in previous longitudinal studies on externalizing behavior may have obscured the presence of continuity of genetic risk. The current study included latent factors representing the latent estimates of externalizing behavior based on both parent and self-report which eliminated rater-specific effects from these latent estimates. Symptoms of externalizing behavior of 1,480 Swedish twin pairs were obtained at ages 8-9, 13-14, 16-17 and 19-20 both by parent and self-report. Mx modeling was used to estimate additive genetic, shared and specific environmental influences. Genetic continuity was found over the entire developmental period as well as additional sources of genetic influence emerging around early and late adolescence. New unique environmental effects (E) on externalizing behavior arose early in adolescence. The results support both the presence of genetic continuity and change in externalizing behavior during adolescence due to newly emerging genetic and environmental risk factors.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Twins
- heritability
- externalizing behavior
- adolescence
- latent modeling
Publication and Content Type
- ref (subject category)
- art (subject category)
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