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  • Abad-Gurumeta, A.Dept Anaesthesia, Hosp Univ la Paz, Madrid, Spain (author)

A systematic review of sugammadex vs neostigmine for reversal of neuromuscular blockade

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2015-11-11
  • Wiley-Blackwell Publishing Inc.2015
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-56286
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-56286URI
  • https://doi.org/10.1111/anae.13277DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • We reviewed systematically sugammadex vs neostigmine for reversing neuromuscular blockade. We included 17 randomised controlled trials with 1553 participants. Sugammadex reduced all signs of residual postoperative paralysis, relative risk (95% CI) 0.46 (0.29-0.71), p=0.0004 and minor respiratory events, relative risk (95% CI) 0.51 (0.32-0.80), p=0.0034. There was no difference in critical respiratory events, relative risk (95% CI) 0.13 (0.02-1.06), p=0.06. Sugammadex reduced drug-related side-effects, relative risk (95% CI) 0.72 (0.54-0.95), p=0.02. There was no difference in the rate of postoperative nausea or the rate of postoperative vomiting, relative risk (95% CI) 0.94 (0.79-1.13), p=0.53, and 0.87 (0.65-1.17), p=0.36 respectively.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Ripolles-Melchor, J.Dept Anaesthesia, Hosp Univ Infanta Leonor, Univ Complutense Madrid, Madrid, Spain (author)
  • Casans-Frances, R.Dept Anaesthesia, Hosp Clin Univ Lozano Blesa, Zaragoza, Spain (author)
  • Espinosa, A.Dept Anaesthesia, Örebro University Hospital, Örebro, Sweden (author)
  • Martinez-Hurtado, E.Dept Anaesthesia, Hosp Univ Infanta Leonor, Univ Complutense Madrid, Madrid, Spain (author)
  • Fernandez-Perez, C.Dept Consultant Prevent Med & Publ Hlth, Univ Complutense Madrid, Madrid, Spain (author)
  • Ramirez, J. M.Dept Colorectal Surg, Univ Zaragoza, Zaragoza, Spain (author)
  • Lopez-Timoneda, F.Hosp Clin San Carlos, Dept Anaesthesia, Univ Complutense Madrid, Madrid, Spain (author)
  • Calvo-Vecino, J. M.Hosp Univ Infanta Leonor, Dept Anaesthesia, Univ Complutense Madrid, Madrid, Spain (author)
  • Dept Anaesthesia, Hosp Univ la Paz, Madrid, SpainDept Anaesthesia, Hosp Univ Infanta Leonor, Univ Complutense Madrid, Madrid, Spain (creator_code:org_t)

Related titles

  • In:Anaesthesia: Wiley-Blackwell Publishing Inc.70:12, s. 1441-14520003-24091365-2044

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