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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006151naa a2200589 4500
001oai:DiVA.org:oru-59137
003SwePub
008170822s2017 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:f86577e5-8c64-4f47-b639-bbcca135544b
009oai:prod.swepub.kib.ki.se:136165422
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-591372 URI
0247 a https://doi.org/10.4244/EIJ-D-16-010212 DOI
0247 a https://lup.lub.lu.se/record/f86577e5-8c64-4f47-b639-bbcca135544b2 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1361654222 URI
040 a (SwePub)orud (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Mohammad, Moman A.u Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-mm11
2451 0a Intravenous beta-blocker therapy in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention is not associated with benefit regarding short-term mortality :b a Swedish nationwide observational study
264 1b Europa Edition,c 2017
338 a print2 rdacarrier
500 a Funding Agencies:SSF (TOTAL-AMI)   Knut and Alice Wallenbergs Foundation  ALF  Skåne University Hospital 
520 a Aims: Our aim was to investigate the impact of intravenous (IV) beta-blocker therapy on short-term mortality and other in-hospital events in patients with ST-segment elevation myocardial infarction (STEMI) treated with dual antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PCI).Methods and results: Using the nationwide Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) registry, we identified all patients with STEMI undergoing PCI between 2006 and 2013. Patients with cardiogenic shock and cardiac arrest at presentation were excluded. The primary endpoint was mortality within 30 days. Secondary endpoints were in-hospital events (mortality, cardiogenic shock and left ventricular ejection fraction [LVEF] <40% at discharge). We adjusted for confounders with a multivariable model and propensity score matching. Out of 16,909 patients, 2,876 (17.0%) were treated with an IV beta-blocker. After adjusting for confounders, the IV beta-blocker group had higher 30-day all-cause mortality (HR: 1.44, 95% CI: 1.14-1.83), more in-hospital cardiogenic shock (OR: 1.53, 95% CI: 1.09-2.16) and were more often discharged with an LVEF <40% (OR: 1.70, 95% CI: 1.51-1.92).Conclusions: In this large nationwide observational study, the use of IV beta-blockers in patients with STEMI treated with primary PCI was associated with higher short-term mortality, lower LVEF at discharge, as well as a higher risk of in-hospital cardiogenic shock.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a adjunctive pharmacotherapy
653 a clinical research
653 a ST-segment elevation myocardial infarction (STEMI)
653 a Adjunctive pharmacotherapy
653 a Clinical research
653 a ST-segment elevation myocardial infarction (STEMI)
7001 a Andell, Pontusu Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-poa
7001 a Koul, Sashau Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-sku
7001 a Desta, Liyewu Karolinska Institutet4 aut
7001 a Jernberg, Tomasu Karolinska Institutet,Karolinska Institute4 aut
7001 a Omerovic, Elmiru Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden; Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden4 aut
7001 a Spaak, Jonasu Karolinska Institutet4 aut
7001 a Fröbert, Ole,d 1964-u Örebro University,Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper,Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)oft
7001 a Jensen, Jensu Karolinska Institutet,Karolinska Institute4 aut
7001 a Engstrøm, Thomasu The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark4 aut0 (Swepub:lu)th4331en
7001 a Hofman-Bang, Claesu Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Persson, Hansu Karolinska Institutet4 aut
7001 a Erlinge, Davidu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kard-der
7102 a Kardiologib Sektion II4 org
7730 t EuroInterventiond : Europa Editiong 13:2, s. E210-E218q 13:2<E210-E218x 1774-024Xx 1969-6213
8564 u http://dx.doi.org/10.4244/EIJ-D-16-01021y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-59137
8564 8u https://doi.org/10.4244/EIJ-D-16-01021
8564 8u https://lup.lub.lu.se/record/f86577e5-8c64-4f47-b639-bbcca135544b
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:136165422

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