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Intensity of smokin...
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Lindblad, Birgitta Ejdervik,1955-Karolinska Institutet
(author)
Intensity of smoking and smoking cessation in relation to risk of cataract extraction : a prospective study of women
- Article/chapterEnglish2005
Publisher, publication year, extent ...
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2005-07-01
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Oxford University Press,2005
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:oru-59249
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-59249URI
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https://doi.org/10.1093/aje/kwi168DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-474636URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:1942855URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The authors investigated the association of smoking and smoking cessation with the incidence of cataract extraction in a population-based prospective cohort study. A total of 34,595 women aged 49-83 years in the Swedish Mammography Cohort were followed from September 1997 through June 2002. Information on smoking, diet, and other lifestyle factors was collected through a self-administered questionnaire. A total of 2,128 cases of age-related cataract extraction were identified. Relative risks were estimated as rate ratios using Cox proportional hazards models. The authors observed a significant dose-response association between intensity of smoking and risk of cataract extraction (among current smokers, p for trend = 0.02; among past smokers, p for trend = 0.0002). After cessation of smoking, the risk decreased with time. Among women with a moderate lifetime smoking intensity (6-10 cigarettes/day), the relative risk was not significantly different from the risk among never smokers 10 years after smoking cessation. Among women who had smoked more intensively (>10 cigarettes/day), after 20 years of nonsmoking the increased risk became small and no longer statistically significant in comparison with never smokers (for trend over time, p < 0.0001). This prospective study confirmed smoking as a risk factor for cataract, with a dose response for smoking intensity. Smoking cessation predicts reduced risk over time, but a longer period of time is needed with a higher smoking intensity.
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Håkansson, NiclasKarolinska Institutet
(author)
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Svensson, HannaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
(author)
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Philipson, BoStockholm Eye Clinic, H. M. Queen Sophia Hospital, Stockholm, Sweden
(author)
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Wolk, AlicjaKarolinska Institutet
(author)
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Karolinska InstitutetDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
(creator_code:org_t)
Related titles
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In:American Journal of Epidemiology: Oxford University Press162:1, s. 73-790002-92621476-6256
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