Search: onr:"swepub:oai:DiVA.org:oru-62907" >
Agreement between i...
Agreement between iFR and FFR in staged follow-up evaluation of non-culprit stenoses after ST-segment elevation myocardial infarction (iSTEMI substudy)
-
- Thim, Troels (author)
- Aarhus University Hospital, Aarhus, Denmark
-
- Götberg, Matthias (author)
- Department of Cardiology, Skåne University Hospital, Lund University, Lund, Sweden
-
- Fröbert, Ole, 1964- (author)
- Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper
-
show more...
-
- Nijveldt, Robin (author)
- Radboud UMC, Nijmegen, Netherlands
-
- van Royen, Niels (author)
- Radboud University, Nijmegen, Netherlands
-
- Baptista, Sergio (author)
- Hospital Fernando Fonseca, Amadora, Portugal
-
- Koul, Sasha (author)
- Department of Cardiology, Skåne University Hospital, Lund University, Lund, Sweden
-
- Kellerth, Thomas (author)
- Örebro University Hospital, Örebro, Sweden
-
- Botker, Hans Erik (author)
- Aarhus University Hospital, Aarhus, Denmark
-
- Christiansen, Evald (author)
- Aarhus University Hospital, Aarhus, Denmark
-
- Jakobsen, Lars (author)
- Aarhus University Hospital, Aarhus, Denmark
-
- Kristensen, Steen Dalby (author)
- Aarhus University Hospital, Aarhus, Denmark
-
- Maeng, Michael (author)
- Aarhus University Hospital, Aarhus, Denmark
-
show less...
-
(creator_code:org_t)
- Elsevier, 2017
- 2017
- English.
-
In: Journal of the American College of Cardiology. - : Elsevier. - 0735-1097 .- 1558-3597. ; 70:18, s. B91-B91
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- BACKGROUND: Classification agreement between instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) is approximately 80% in stable patients. It was recently shown that FFR guidance, as compared to iFR guidance, was associated with a higher risk of subsequent revascularization among patients with non- ST-segment elevation myocardial infarction. The classification agreement, and the impact of time interval, between iFR and FFR in the assessment of non-culprit lesions after recent ST-segment elevation myocardial infarction (STEMI) has not been described.METHODS: The iSTEMI study assessed agreement between iFR across non-culprit stenoses at the index procedure in patients with STEMI versus iFR and FFR at a follow-up angiography. The interval between STEMI and follow-up evaluation was at the discretion of the treating physicians. In this substudy, classification agreement between follow-up iFR and follow-up FFR was evaluated within groups defined according to follow-up time point after STEMI, i.e., <5days, 5-15days, and16 days. iFR<0.90 and FFR0.80 were considered hemodynamically significant.RESULTS: Among 120 patients with 157 non-culprit stenoses, follow-up iFR and FFR was available in 112 patients with 146 non-culprit stenoses. Median follow-up interval was 16 days (IQR 5-32 days). The overall classification agreement was 84%. With follow-up<5days after STEMI, there was classification agreement between iFR and FFR was in 27 of 35 (77%) non-culprit stenoses. With follow-up 5-15 after STEMI, there was classification agreement in 33 of 38 (86%) non-culprit stenoses. With follow-up 16 days after STEMI, there was classification agreement in 63 of 73 (86%) non-culprit stenoses. The observed differences in these proportions over time after STEMI were not statistically significant (<5versus5days, p¼0.19).CONCLUSION: Overall, classification agreement between iFR and FFR in the assessment of non-culprit lesions after STEMI was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between follow-up iFR and follow-up FFR, although the observed differences were not statistically significant.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- vet (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Thim, Troels
-
Götberg, Matthia ...
-
Fröbert, Ole, 19 ...
-
Nijveldt, Robin
-
van Royen, Niels
-
Baptista, Sergio
-
show more...
-
Koul, Sasha
-
Kellerth, Thomas
-
Botker, Hans Eri ...
-
Christiansen, Ev ...
-
Jakobsen, Lars
-
Kristensen, Stee ...
-
Maeng, Michael
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
- Articles in the publication
-
Journal of the A ...
- By the university
-
Örebro University