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Availability of hep...
Availability of hepatitis C diagnostics and therapeutics in European and Eurasia countries
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- Leblebicioglu, Hakan (author)
- Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University, Medical School, Samsun, Turkey
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- Arends, Joop E. (author)
- Internal Medicine and Infectious Diseases, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands
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- Ozaras, Resat (author)
- Department of Infectious Diseases and Clinical Microbiology, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey
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- Corti, Giampaolo (author)
- Infectious Disease Unit, University of Florence School of Medicine, Florence, Italy
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- Santos, Lurdes (author)
- Infectious Diseases Service C Hospitalar São João, Faculty of Medicine, Alameda Professor Hernani Monteiro, Porto, Portugal
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- Boesecke, Christoph (author)
- Department of Medicine I, Bonn University, Bonn, Germany
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- Ustianowski, Andrew (author)
- Infectious Diseases & Tropical Medicine and Research Lead, North Western Infectious Diseases Unit, Pennine Acute Hospitals NHS Trust, North Manchester General Hospital, Manchester, UK
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- Duberg, Ann-Sofi, 1957- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Infectious Diseases, Örebro University Hospital, Örebro, Sweden
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- Ruta, Simona (author)
- Stefan S. Nicolau Institute of Virology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
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- Salkic, Nermin N. (author)
- Department of Gastroenterology and Hepatology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina
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- Husa, Petr (author)
- Infectious Diseases, Masaryk University, Brno, Czech Republic; Infectious Diseases, University Hospital Brno, Brno, Czech Republic
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- Lazarevic, Ivana (author)
- Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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- Pineda, Juan A. (author)
- Unidad de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain
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- Pshenichnaya, Natalia Yurievna (author)
- Rostov State Medical University, Rostov-on-Don, Russia
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- Tsertswadze, Tengiz (author)
- Infectious Diseases, AIDS and Clinical Immunology Research Center, Tbilisi, Georgia; Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia
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- Matičič, Mojca (author)
- Clinic for Infectious Diseases and Febrile Illnesses, University Medical Centre, Ljubljana, Slovenia
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- Puca, Edmond (author)
- Department of Infection Diseases, University Hospital Center, Tirane, Albania
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- Abuova, Gulzhan (author)
- Infectious Diseases Department, South - Kazakhstan State Pharmaceutical Academy, Shymkent, Kazakhstan
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- Gervain, Judit (author)
- Division Hepato-Pancreatology, 1st Department of Gastroenterology and Molecular Diagnostic Laboratory, "Szent György" Teaching Hospital Székesfehérvár, Székesfehérvár, HungaryDivision Hepato-Pancreatology, 1st Department of Gastroenterology and Molecular Diagnostic Laboratory, "Szent György" Teaching Hospital Székesfehérvár, Székesfehérvár, Hungary
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- Bayramli, Ramin (author)
- Department of Microbiology and Immunology, Azerbaijan Medical University, Educational Therapeutic Hospital, Baku, Azerbaijan
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- Ahmeti, Salih (author)
- Infectious Disease Clinic, University Clinical Centre of Kosova, Faculty of Medicine, Prishtina University, Pristina, Kosovo
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- Koulentaki, Mairi (author)
- Department of Gastroenterology, University Hospital of Heraklion, Heraklion, Crete, Greece
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- Kilani, Badreddine (author)
- Service des Maladies Infectieuses, Faculté de Médecine de Tunis, Université Tunis EL Manar, Hôpital la Rabta, Tunis, Tunisia
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- Vince, Adriana (author)
- University Hospital of Infectious Diseases, Zagreb School of Medicine, Zagreb, Croatia
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- Negro, Francesco (author)
- Divisions of Gastroenterology and Hepatology of Clinical Pathology, University Hospital of Geneva, Geneva, Switzerland
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- Sunbul, Mustafa (author)
- Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University, Medical School, Samsun, Turkey
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- Salmon, Dominique (author)
- Infectious Diseases, Hôpitaux Universitaires Paris Centre, Université Paris Descartes, Paris, France
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(creator_code:org_t)
- Amsterdam, Netherlands : Elsevier, 2018
- 2018
- English.
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In: Antiviral Research. - Amsterdam, Netherlands : Elsevier. - 0166-3542 .- 1872-9096. ; 150, s. 9-14
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- BACKGROUND: Treatment with direct acting antiviral agents (DAAs) has provided sustained virological response rates in >95% of patients with chronic hepatitis C virus (HCV) infection. However treatment is costly and market access, reimbursement and governmental restrictions differ among countries. We aimed to analyze these differences among European and Eurasian countries.METHODS: A survey including 20-item questionnaire was sent to experts in viral hepatitis. Countries were evaluated according to their income categories by the World Bank stratification.RESULTS: Experts from 26 countries responded to the survey. As of May 2016, HCV prevalence was reported as low (≤1%) in Croatia, Czech Republic, Denmark, France, Germany, Hungary, the Netherlands, Portugal, Slovenia, Spain, Sweden, UK; intermediate (1-4%) in Azerbaijan, Bosnia and Herzegovina, Italy, Kosovo, Greece, Kazakhstan, Romania, Russia, Serbia and high in Georgia (6.7%). All countries had national guidelines except Albania, Kosovo, Serbia, Tunisia, and UK. Transient elastography was available in all countries, but reimbursed in 61%. HCV-RNA was reimbursed in 81%. PegIFN/RBV was reimbursed in 54% of the countries. No DAAs were available in four countries: Kazakhstan, Kosovo, Serbia, and Tunisia. In others, at least one DAA combination with either PegIFN/RBV or another DAA was available. In Germany and the Netherlands all DAAs were reimbursed without restrictions: Sofosbuvir and sofosbuvir/ledipasvir were free of charge in Georgia.CONCLUSION: Prevalence of HCV is relatively higher in lower-middle and upper-middle income countries. DAAs are not available or reimbursed in many Eurasia and European countries. Effective screening and access to care are essential for reducing liver-related morbidity and mortality.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Keyword
- Availability of hepatitis C diagnostics
- Therapeutics in European and Eurasia countries
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Leblebicioglu, H ...
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Arends, Joop E.
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Ozaras, Resat
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Corti, Giampaolo
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Santos, Lurdes
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Boesecke, Christ ...
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show more...
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Ustianowski, And ...
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Duberg, Ann-Sofi ...
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Ruta, Simona
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Salkic, Nermin N ...
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Husa, Petr
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Lazarevic, Ivana
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Pineda, Juan A.
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Pshenichnaya, Na ...
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Tsertswadze, Ten ...
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Matičič, Mojca
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Puca, Edmond
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Abuova, Gulzhan
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Gervain, Judit
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Bayramli, Ramin
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Ahmeti, Salih
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Koulentaki, Mair ...
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Kilani, Badreddi ...
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Vince, Adriana
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Negro, Francesco
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Sunbul, Mustafa
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Salmon, Dominiqu ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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MEDICAL AND HEAL ...
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Antiviral Resear ...
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Örebro University