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Elective abdominal ...
Elective abdominal surgery alters the free amino acid content of the human intestinal mucosa
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- Ahlman, B. (author)
- Department of Surgery, Karolinska Hospital, Sweden
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Andersson, K. (author)
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- Ljungqvist, Olle, 1954- (author)
- Karolinska Institutet
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Persson, B. (author)
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- Wernerman, J. (author)
- Karolinska Institutet
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(creator_code:org_t)
- Stockholm, Sweden : Taylor & Francis, 1995
- 1995
- English.
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In: European Journal of Surgery. - Stockholm, Sweden : Taylor & Francis. - 1102-4151 .- 1741-9271. ; 161:8, s. 593-601
- Related links:
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Objective: To assess the impact of a standard moderately severe surgical operation on the mucosal amino acid content of the duodenum and the colon.Design: Open study.Setting: University hospital, Sweden.Subjects: Nine patients who were to undergo elective open cholecystectomy.Interventions: Endoscopically obtained biopsy specimens from the intestinal mucosa. Main outcome measures: Changes in the content of free amino acids in the duodenum and colon at three days postoperatively.Results: The concentration of glutamine in the duodenum increased by 27% and that of glutamic acid by 34% after operation, whereas their content in colon remained unaltered. The concentration of branched chain amino acids increased by 26% in the duodenal mucosa after operation and by 24% in the colonic mucosa. The total concentration of amino acids (excluding taurine) increased by 9% in the duodenum, but remained unaltered in the colon.Conclusion: This study shows characteristic and consistent alterations in the free amino acid content of the intestinal tract after a moderately severe operation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Free amino acids
- human intestinal mucosa
- protein content
- endoscopy
- biopsy specimen
- abdominal operation
Publication and Content Type
- ref (subject category)
- art (subject category)
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