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Disposable bioanalytical microdevice for monitoring the effect of anti-platelet drugs

Basabe-Desmonts, L. (author)
Biomedical Diagnostics Institute (BDI), Dublin City University, Dublin, Ireland; Biomedical Diagnostics Institute Programme, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland
Ramström, Sofia, 1973- (author)
Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet,Royal College of Surgeons in Ireland, Dublin
Lopez-Alonso, A. (author)
Biomedical Diagnostics Institute Programme, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland
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Somers, M. (author)
Biomedical Diagnostics Institute (BDI), Dublin City University, Dublin, Ireland
Ricco, A. J. (author)
Biomedical Diagnostics Institute (BDI), Dublin City University, Dublin, Ireland
Kenny, D. (author)
Biomedical Diagnostics Institute Programme, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland
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 (creator_code:org_t)
CBMS, 2010
2010
English.
In: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. - : CBMS. - 9781618390622 ; , s. 1388-1390
  • Conference paper (peer-reviewed)
Abstract Subject headings
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  • We report a disposable self-powered integrated microfluidic chip that enables a rapid and simple platelet-function assay from small samples of whole blood. The chip integrates a single-cell adhesion assay with a microfluidic platform; it enables accurate quantification of platelet adhesion, and it controls whole blood flow rate, shear stress, volume of sample, and assay time.

Subject headings

NATURVETENSKAP  -- Biologi -- Cellbiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Cell Biology (hsv//eng)

Keyword

Cardiovascular
Disposable
Platelets
Point of care
Self-powered microfluidics
Whole blood
Self-powered
Cell adhesion
Microfluidics

Publication and Content Type

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