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  • Everhov, Åsa H.Karolinska Institutet,Karolinska Inst, Sweden (author)

Work Loss Before and After Diagnosis of Crohn's Disease

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • 2018-12-14
  • Oxford University Press,2019
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-70799
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-70799URI
  • https://doi.org/10.1093/ibd/izy382DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:141280215URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158935URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies:Karolinska Institutet (KI SOS)Swedish Medical Society (Fund for Research in Gastroenterology)  Swedish Medical Society (Ihre Foundation)  Stiftelsen Tornspiran  Mag-tarmfonden  Jane and Dan Olsson Foundation  Mjölkdroppen Foundation  Bengt Ihre Research Fellowship in Gastroenterology 
  • Funding Agencies|Karolinska Institutet (KI SOS); Swedish Research Council; Swedish Cancer Society; Heart Lung Foundation; Swedish Medical Society; Swedish Medical Society (Fund for Research in Gastroenterology); Swedish Medical Society (Ihre Foundation); Stiftelsen Tornspiran; Mag-tarmfonden; Jane and Dan Olsson Foundation; Mjolkdroppen Foundation; Bengt Ihre Research Fellowship in Gastroenterology; Karolinska Institutet; Stockholm County Council
  • Background: The aim of this study was to examine work loss in patients with Crohn's disease.Methods: Using nationwide registers, we identified incident patients with Crohn's disease (2007-2010) and population comparator subjects without inflammatory bowel disease, matched by age, sex, calendar year, health care region, and education level. We assessed the number of lost workdays due to sick leave and disability pension from 5 years before to 5 years after first diagnosis of Crohn's disease or end of follow-up (September 30, 2015).Results: Among the 2015 incident Crohn's disease patients (median age, 35 years; 50% women), both the proportion with work loss and the mean annual number of lost workdays were larger 5 years before diagnosis (25%; mean, 45 days) than in the 10,067 comparators (17%; mean, 29 days). Increased work loss was seen during the year of diagnosis, after which it declined to levels similar to before diagnosis. Of all patients, 75% had no work loss 24-12 months before diagnosis. Of them, 84% had full work ability also 12-24 months after diagnosis. In patients with total work loss (8.3% of all) before diagnosis, 83% did not work after. Among those with full work ability before diagnosis, the absolute risk of having total work loss after diagnosis was 1.4% (0.43% in the comparators). Our results were consistent across several sensitivity analyses using alternative definitions for date of diagnosis.Conclusions: Patients with Crohn's disease had increased work loss several years before diagnosis, possibly explained by comorbidity or by diagnostic delay.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Khalili, HamedClinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastroenterology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Masschusetts, USA,Karolinska Inst, Sweden; Harvard Med Sch, MA 02115 USA (author)
  • Askling, JohanKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Myrelid, PärLinköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)parmy24 (author)
  • Ludvigsson, Jonas F.,1969-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro University, Örebro, Sweden,Karolinska Inst, Sweden; Orebro Univ Hosp, Sweden(Swepub:oru)jsln (author)
  • Halfvarson, Jonas,1970-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Gastroenterology,Orebro Univ, Sweden(Swepub:oru)jshn (author)
  • Nordenvall, CarolineKarolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden (author)
  • Neovius, MartinKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Söderling, JonasKarolinska Institutet,Karolinska Inst, Sweden (author)
  • Olén, OlaKarolinska Institutet,Karolinska Inst, Sweden; Sachs Children and Youth Hosp, Sweden (author)
  • Karolinska InstitutetKarolinska Inst, Sweden (creator_code:org_t)

Related titles

  • In:Inflammatory Bowel Diseases: Oxford University Press25:7, s. 1237-12471078-09981536-4844

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