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An integrative appr...
An integrative approach for biological data mining and visualisation
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- Gopalacharyulu, Peddinti V. (author)
- VTT Technical Research Centre of Finland, Espoo, Finland
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- Lindfors, Erno (author)
- VTT Technical Research Centre of Finland, Espoo, Finland
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- Miettinen, Jarkko (author)
- VTT Technical Research Centre of Finland, Espoo, Finland
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- Bounsaythip, Catherine K. (author)
- VTT Technical Research Centre of Finland, Espoo, Finland
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- Oresic, Matej, 1967- (author)
- VTT Technical Research Centre of Finland, Espoo, Finland
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(creator_code:org_t)
- Inderscience Publishers, 2008
- 2008
- English.
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In: International Journal of Data Mining and Bioinformatics. - : Inderscience Publishers. - 1748-5673 .- 1748-5681. ; 2:1, s. 54-77
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The emergence of systems biology necessitates development of platforms to organise and interpret plentitude of biological data. We present a system to integrate data across multiple bioinformatics databases and enable mining across various conceptual levels of biological information. The results are represented as complex networks. Context dependent mining of these networks is achieved by use of distances. Our approach is demonstrated with three applications: full metabolic network retrieval with network topology study, exploration of properties and relationships of a set of selected proteins, and combined visualisation and exploration of gene expression data with related pathways and ontologies.
Subject headings
- NATURVETENSKAP -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)
Keyword
- Data mining
- bioinformatics
- complex networks
- heterogeneous database integration
- systems biology
Publication and Content Type
- ref (subject category)
- art (subject category)
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