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  • Faxen-Irving, GerdKarolinska Institutet (author)

Does Fatty Acid Composition in Subcutaneous Adipose Tissue Differ between Patients with Alzheimer's Disease and Cohabiting Proxies?

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • IOS Press,2018
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-74038
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-74038URI
  • https://doi.org/10.3233/JAD-170359DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343881URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:137471707URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding agencies:Stockholm County CouncilKarolinska InstitutetMedical Research CouncilFunds of CapioDemensförbundetGamla TjänarinnorSwedish Alzheimer FoundationOdd FellowSwedish Nutrition FoundationGun och Bertil Stohnes StiftelseSwedish Society of PhysiciansLion's Sweden
  • Low tissue levels of the major marine ω3 fatty acids (FAs) DHA and EPA are found in Alzheimer's disease (AD). We investigated if healthy proxies to AD patients have higher levels of these ω3 FAs. We observed lower levels of EPA and DHA in subcutaneous adipose tissue biopsies from 64 AD patients compared with 16 cognitively healthy proxies. No significant difference was observed when pairwise comparisons were made between a subset of 16 AD patients and their co-habiting proxies. Larger studies are needed to replicate these findings and to determine if they could depend on FA intake or differences in metabolism.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Falahati, FarshadKarolinska Institutet (author)
  • Basun, HansUppsala universitet,Geriatrik(Swepub:uu)habas169 (author)
  • Eriksdotter, MariaKarolinska Institutet (author)
  • Vedin, IngerDepartment of Medicine, Division of Hematology, Department of NVS, Karolinska Institutet, Huddinge, Sweden,Karolinska Inst, Dept NVS, Dept Med, Div Hematol, Huddinge (author)
  • Wahlund, Lars-OlofKarolinska Institutet (author)
  • Schultzberg, MarianneKarolinska Institutet (author)
  • Hjorth, ErikKarolinska Institutet (author)
  • Palmblad, JanKarolinska Institutet (author)
  • Cederholm, TommyKarolinska Institutet,Uppsala universitet,Klinisk nutrition och metabolism,Akad Sjukhuset, Dept Geriatr Med, Uppsala(Swepub:uu)tomce419 (author)
  • Freund-Levi, Yvonne,1956-Department of Neurobiology, Care Sciences and Society (NVS), Division of Clinical Geriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatrics, Karolinska University Hospital, Huddinge, Sweden,Karolinska Inst, Div Clin Geriatr, Dept Neurobiol Care Sci & Soc NVS, Huddinge; Karolinska Univ Hosp, Dept Geriatr, Huddinge(Swepub:oru)yfi (author)
  • Karolinska InstitutetGeriatrik (creator_code:org_t)

Related titles

  • In:Journal of Alzheimer's Disease: IOS Press61:2, s. 515-5191387-28771875-8908

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