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Correlating the Bet...
Correlating the Bethesda System for Reporting Thyroid Cytopathology with Histology and Extent of Surgery : A Review of 21,746 Patients from Four Endocrine Surgery Registries Across Two Continents
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- Inabnet, William B., 3rd (author)
- Department of Surgery, University of Kentucky College of Medicine, Lexington, KY, USA
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- Palazzo, Fausto (author)
- Hammersmith Hospital and Imperial College, London, UK
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- Sosa, Julie Ann (author)
- University of California, San Francisco, CA, USA
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- Kriger, Joshua (author)
- Columbia University Mailman School of Public Health, New York, NY, USA
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- Aspinall, Sebastian (author)
- Aberdeen Royal Infirmary, Aberdeen, Scotland, UK
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- Barczynski, Marcin (author)
- Department of Endocrine Surgery, Third Chair of General Surgery, Jagiellonian University Medical College, Krakow, Poland
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- Doherty, Gerard (author)
- Brigham and Women's Hospital, Boston, MA, USA,Brigham and Women's Hospital / Harvard Medical School
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- Iacobone, Maurizio (author)
- University of Padua, Padua, Italy
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- Nordenstrom, Erik (author)
- Lund University,Lunds universitet,Endokrin- och sarkomkirurgi,Forskargrupper vid Lunds universitet,Endocrine and Sarcoma Surgery,Lund University Research Groups
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- Scott-Coombes, David (author)
- University Hospital of Wales, Cardiff, UK
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- Wallin, Göran, 1952- (author)
- Karolinska Institutet,Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper
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- Williams, Lauren (author)
- Columbia University Mailman School of Public Health, New York, NY, USA
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- Bray, Rachel (author)
- Columbia University Mailman School of Public Health, New York, NY, USA
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- Bergenfelz, Anders (author)
- Lund University,Lunds universitet,Endokrin- och sarkomkirurgi,Forskargrupper vid Lunds universitet,Endocrine and Sarcoma Surgery,Lund University Research Groups
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(creator_code:org_t)
- 2019-11-05
- 2020
- English.
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In: World Journal of Surgery. - : Springer. - 0364-2313 .- 1432-2323. ; 44:2, s. 426-435
- Related links:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
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- BACKGROUND: The Bethesda system for cytopathology (TBSRTC) is a 6-tier diagnostic framework developed to standardize thyroid cytopathology reporting. The aim of this study was to determine the risk of malignancy (ROM) for each Bethesda category.METHODS: Thyroidectomy-related data from 314 facilities in 22 countries were entered into the following outcome registries: CESQIP (North America), Eurocrine (Europe), SQRTPA (Sweden) and UKRETS (UK). Demographic, cytological, pathologic and extent of surgery data were mapped into one dataset and analyzed.RESULTS: Out of 41,294 thyroidectomy patient entries from January 1, 2015, to June 30, 2017, 21,746 patients underwent both thyroid FNA and surgery. A comparison of cytology and surgical pathology data demonstrated a ROM for Bethesda categories 1 to 6 of 19.2%, 12.7%, 31.9%, 31.4%, 77.8% and 96.0%, respectively. Male patients had a higher rate of malignancy for every Bethesda category. Secondary analysis demonstrated a high ROM in male patients with Bethesda 3 category aged 31-35 years (52.1%, 95% confidence interval (CI) 37.9-66.2%), aged 36-40 years (55.9%, 95% CI 39.2-72.6%) and aged 41-45 years (46.9%, 95% CI 33-60.9%). Patients with Bethesda 5 and 6 scores were more likely to undergo total thyroidectomy (65.9% and 84.6%); for patients with Bethesda scores 2 and 3, a higher percentage of females underwent total thyroidectomy compared to males in spite of a higher ROM for males.CONCLUSIONS: These data demonstrate that Bethesda categories 1-4 are associated with a higher ROM compared to the first edition of TBSRTC, especially in male patients, and validate findings from the second edition of TBSRTC.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
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- art (subject category)
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- By the author/editor
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Inabnet, William ...
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Palazzo, Fausto
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Sosa, Julie Ann
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Kriger, Joshua
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Aspinall, Sebast ...
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Barczynski, Marc ...
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show more...
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Doherty, Gerard
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Iacobone, Mauriz ...
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Nordenstrom, Eri ...
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Scott-Coombes, D ...
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Wallin, Göran, 1 ...
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Williams, Lauren
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Bray, Rachel
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Bergenfelz, Ande ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
- Articles in the publication
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World Journal of ...
- By the university
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Örebro University
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Lund University
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Karolinska Institutet