Impact of healthy diet and physical activity on metabolic health in men and women: Study Protocol Clinical Trial (SPIRIT Compliant)

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Bergens, Oscar,1991-Örebro universitet,Institutionen för hälsovetenskaper (author)

Impact of healthy diet and physical activity on metabolic health in men and women : Study Protocol Clinical Trial (SPIRIT Compliant)

Article/chapterEnglish2020

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Wolters Kluwer,2020
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LIBRIS-ID:oai:DiVA.org:oru-83948
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-83948URI
https://doi.org/10.1097/MD.0000000000019584DOI

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Language:English
Summary in:English

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Subject category:art swepub-publicationtype

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Funding Agencies:EU HORIZON 2020 Research and Innovation Programme (European Joint Programming Initiative "A healthy diet for a healthy life" "JPI HDHL") EU HORIZON 2020 Research and Innovation Programme (ERA-NET co-fund HDHL-INTIMIC) 727565
Introduction: Healthy dietary patterns and physical activity (PA) represent important lifestyle behaviors with considerable potential to influence on age-related metabolic health. Yet, data on the combined effects of these lifestyle behaviors on metabolic health including low-grade systemic inflammation in aging populations remain scarce. Therefore, this protocol describes a randomized controlled trial aiming to examine the impacts of healthy dietary patterns alone or combined with PA on metabolic health in middle-aged and older men and women. Material and methods: The ORUDIET study is a 3-arm randomized controlled 16-week trial: Healthy Diet (HD), Healthy diet plus PA (HD-PA), and control (CON). The trial is open label, randomized with allocation concealment, parallel groups with passive controls. Participants without overt disease aged between 55 and 70 years, with BMI below 35, a current intake of a maximum of 1 serving of fruit and vegetable per day, and noncompliance to PA guidelines are eligible for inclusion. Participants in HD are instructed to increase fruit and vegetable intake to 5 servings per day (equivalent to 500 g). Participants in HD-PA receive the same dietary intervention as the HD and are additionally instructed to engage in moderate-to-vigorous physical activities for at least 150 minutes per week. The primary study outcomes are changes in metabolic and inflammatory health biomarkers. Secondary outcomes are changes in body composition and perceived health. Ethics and dissemination: The study protocol has been approved by the ethical review board in Uppsala, Sweden. The results will be published in peer-reviewed journals and disseminated in national and international conferences.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Idrottsvetenskap hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Sport and Fitness Sciences hsv//eng
aging
body composition
exercise
healthy diet
metabolic syndrome
systemic inflammation

Added entries (persons, corporate bodies, meetings, titles ...)

Veen, Jort,1975-Örebro universitet,Institutionen för hälsovetenskaper(Swepub:oru)jtvn (author)
Montiel Rojas, Diego,1984-Örebro universitet,Institutionen för hälsovetenskaper(Swepub:oru)dml (author)
Edholm, Peter,1977-Örebro universitet,Institutionen för hälsovetenskaper(Swepub:oru)pmd (author)
Kadi, Fawzi,1970-Örebro universitet,Institutionen för hälsovetenskaper(Swepub:oru)fki (author)
Nilsson, Andreas,1973-Örebro universitet,Institutionen för hälsovetenskaper(Swepub:oru)asnn (author)
Örebro universitetInstitutionen för hälsovetenskaper (creator_code:org_t)

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