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Instantaneous wave-...
Instantaneous wave-free ratio cutoff values for nonculprit stenosis classification in patients with ST-segment elevation myocardial infarction (an iSTEMI substudy)
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- Thim, Troels (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Götberg, Matthias (author)
- Department of Cardiology, Skåne University Hospital, Sweden
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- Fröbert, Ole, 1964- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology
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- Nijveldt, Robin (author)
- Department of Cardiology, VU University Medical Center, Netherlands
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- van Royen, Niels (author)
- Department of Cardiology, VU University Medical Center, Netherlands
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- Baptista, Sergio Bravo (author)
- Hospital Prof. Doutor Fernando da Fonseca, Cardiology Department, Amadora, Portugal; University Clinic of Cardiology, Faculty of Medicine at University of Lisbon, Portugal
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- Koul, Sasha (author)
- Department of Cardiology, Skåne University Hospital, Sweden
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- Kellerth, Thomas (author)
- Department of Cardiology, Örebro University, Sweden, Sweden
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- Bøtker, Hans Erik (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Terkelsen, Christian Juhl (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Christiansen, Evald Høj (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Jakobsen, Lars (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Kristensen, Steen Dalby (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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- Maeng, Michael (author)
- Department of Cardiology, Aarhus University Hospital, Denmark
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(creator_code:org_t)
- Lippincott Williams & Wilkins, 2020
- 2020
- English.
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In: Coronary Artery Disease. - : Lippincott Williams & Wilkins. - 0954-6928 .- 1473-5830. ; 31:5, s. 411-416
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Objectives: The instantaneous wave-free ratio cutoff value of <0.90 for hemodynamic significance of coronary stenoses has been validated in stable patients. We examined different cutoff values in the evaluation of nonculprit stenoses in patients with ST-segment elevation myocardial infarction.Methods: We measured instantaneous wave-free ratio across nonculprit stenoses in the acute setting and at follow-up in 120 patients with ST-segment elevation myocardial infarction and 157 nonculprit stenoses, of which, 113 patients with 147 nonculprit stenoses completed follow-up.Results: The prevalence of nonculprit stenosis hemodynamic significance was 52% in the acute setting and 41% at follow-up. With follow-up, instantaneous wave-free ratio as reference, acute instantaneous wave-free ratio >0.90 had a negative predictive value of 89%. Acute instantaneous wave-free ratio <0.90 had a positive predictive value of 68%. Acute instantaneous wave-free ratio >0.93 had a negative predictive value of 100%. Acute instantaneous wave-free ratio <0.86 and <0.83 had positive predictive values of 71 and 77%. Using acute instantaneous wave-free ratio <0.90 as cutoff for hemodynamic significance yielded the highest degree of classification agreement between acute and follow-up instantaneous wave-free ratio.Conclusions: In patients with ST-segment elevation myocardial infarction, acute instantaneous wave-free ratio with the cutoff values <0.90 for hemodynamic significance appears optimal in the evaluation of nonculprit stenoses and has a high negative predictive value and a moderate positive predictive value.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- instantaneous wave-free ratio
- nonculprit stenosis
- ST-segment elevation myocardial infarction
Publication and Content Type
- ref (subject category)
- art (subject category)
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Thim, Troels
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Götberg, Matthia ...
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Fröbert, Ole, 19 ...
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Nijveldt, Robin
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van Royen, Niels
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Baptista, Sergio ...
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Koul, Sasha
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Kellerth, Thomas
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Bøtker, Hans Eri ...
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Terkelsen, Chris ...
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Christiansen, Ev ...
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Jakobsen, Lars
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Kristensen, Stee ...
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Maeng, Michael
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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Coronary Artery ...
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Örebro University