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Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)

Thim, Troels (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Götberg, Matthias (author)
Department of Cardiology, Skåne University Hospital, Malmö, Sweden
Fröbert, Ole, 1964- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology
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Nijveldt, Robin (author)
Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands
van Royen, Niels (author)
Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands
Baptista, Sergio Bravo (author)
Cardiology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal
Koul, Sasha (author)
Department of Cardiology, Skåne University Hospital, Malmö, Sweden
Kellerth, Thomas (author)
Department of Cardiology, Örebro University, Örebro, Sweden
Bøtker, Hans Erik (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Terkelsen, Christian Juhl (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Christiansen, Evald Høj (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Jakobsen, Lars (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Kristensen, Steen Dalby (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
Maeng, Michael (author)
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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 (creator_code:org_t)
2020-09-01
2020
English.
In: BMC Research Notes. - : BioMed Central. - 1756-0500. ; 13:1
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI).RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5-32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

FFR
Fractional flow reserve
Instantaneous wave-free ration
Nonculprit stenosis
ST-segment elevation myocardial infarction
iFR

Publication and Content Type

ref (subject category)
art (subject category)

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