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  • Krebs, GeorginaKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK; National and Specialist OCD and Related Disorders Clinic for Young People, South London, UK; Maudsley NHS Foundation Trust, London, UK (author)

The association between body dysmorphic symptoms and suicidality among adolescents and young adults : a genetically informative study

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • Cambridge University Press,2022
  • printrdacarrier

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  • LIBRIS-ID:oai:DiVA.org:oru-85868
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-85868URI
  • https://doi.org/10.1017/S0033291720002998DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:149731576URI
  • https://gup.ub.gu.se/publication/302293URI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

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  • Funding agencies:UK Research & Innovation (UKRI)Medical Research Council UK (MRC) MR/N001400/1 MR/M021475/1  General Electric
  • BACKGROUND: Previous research indicates that body dysmorphic disorder (BDD) is associated with risk of suicidality. However, studies have relied on small and/or specialist samples and largely focussed on adults, despite these difficulties commonly emerging in youth. Furthermore, the aetiology of the relationship remains unknown.METHODS: Two independent twin samples were identified through the Child and Adolescent Twin Study in Sweden, at ages 18 (N = 6027) and 24 (N = 3454). Participants completed a self-report measure of BDD symptom severity. Young people and parents completed items assessing suicidal ideation/behaviours. Logistic regression models tested the association of suicidality outcomes with: (a) probable BDD, classified using an empirically derived cut-off; and (b) continuous scores of BDD symptoms. Bivariate genetic models examined the aetiology of the association between BDD symptoms and suicidality at both ages.RESULTS: Suicidal ideation and behaviours were common among those with probable BDD at both ages. BDD symptoms, measured continuously, were linked with all aspects of suicidality, and associations generally remained significant after adjusting for depressive and anxiety symptoms. Genetic factors accounted for most of the covariance between BDD symptoms and suicidality (72.9 and 77.7% at ages 18 and 24, respectively), but with significant non-shared environmental influences (27.1 and 22.3% at ages 18 and 24, respectively).CONCLUSIONS: BDD symptoms are associated with a substantial risk of suicidal ideation and behaviours in late adolescence and early adulthood. This relationship is largely explained by common genetic liability, but non-shared environmental effects are also significant and could provide opportunities for prevention among those at high-risk.

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  • Fernández de la Cruz, LorenaKarolinska Institutet (author)
  • Rijsdijk, Frühling V.King's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK (author)
  • Rautio, DanielKarolinska Institutet (author)
  • Enander, JesperKarolinska Institutet (author)
  • Rück, ChristianKarolinska Institutet (author)
  • Lichtenstein, PaulKarolinska Institutet (author)
  • Lundström, SebastianGothenburg University,Göteborgs universitet,Gillbergcentrum,Centrum för etik, juridik och mental hälsa,Gillberg Neuropsychiatry Centre,Centre for Ethics, Law, and Mental Health(Swepub:gu)xluseb (author)
  • Larsson, Henrik,1975-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden(Swepub:oru)hiln (author)
  • Eley, Thalia C.King's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK (author)
  • Mataix-Cols, DavidKarolinska Institutet (author)
  • Karolinska InstitutetKing's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK; National and Specialist OCD and Related Disorders Clinic for Young People, South London, UK; Maudsley NHS Foundation Trust, London, UK (creator_code:org_t)

Related titles

  • In:Psychological Medicine: Cambridge University Press52:7, s. 1268-12760033-29171469-8978

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