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Mental Disorders in...
Mental Disorders in Peyronie's Disease : A Swedish Cohort Study of 3.5 Million Men
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- Kuja-Halkola, Ralf (author)
- Karolinska Institutet
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- Henningsohn, Lars (author)
- Karolinska Institutet
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- D'Onofrio, Brian M. (author)
- Karolinska Institutet
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- Mills, Jesse (author)
- Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, California
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- Adolfsson, Annsofie, Universitetslektor, 1960- (author)
- Örebro universitet,Institutionen för hälsovetenskaper
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- Larsson, Henrik, 1975- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper
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- Martin, Cederlöf, 1980- (author)
- Karolinska Institutet
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(creator_code:org_t)
- American Urological Association, Inc. 2021
- 2021
- English.
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In: Journal of Urology. - : American Urological Association, Inc.. - 0022-5347 .- 1527-3792. ; 205:3, s. 864-869
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- PURPOSE: Studies have shown that men with Peyronie's disease often suffer from psychological problems, but the psychiatric burden of this disorder remains largely unknown. We assessed risks of a range of psychiatric outcomes in a population-based, Swedish cohort comprising 3.5 million men.MATERIALS AND METHODS: We conducted a longitudinal cohort study based on Swedish national registers. A total of 8,105 men diagnosed with Peyronie's disease and 3.5 million comparison subjects from the general Swedish population were selected, and followed-up for diagnosed psychiatric outcomes, including substance use disorder, alcohol misuse, anxiety disorder, depression, and self-injurious behaviors. Risks of psychiatric outcomes were estimated with Cox regressions, and additionally adjusted for birth year.RESULTS: Men with Peyronie's disease had increased risks of being diagnosed with substance use disorder; hazard ratio (HR) 1.4, 95% confidence interval (CI) 1.1-1.9, no excess risk of alcohol misuse; HR 0.9, CI 0.8-1.1, but elevated risks of anxiety disorder; HR 1.9, CI 1.6-2.2, depression; HR 1.7, CI 1.5-2.0, self-injurious behaviors; HR 2.0, 95% CI 1.7-2.3, as well as any psychiatric outcomes; HR 1.4, 95% CI 1.2-1.5. The risk estimates were slightly decreased when adjusted for birth year. A limitation of the study was that we had no information about Peyronie's disease diagnoses assigned before year 1997.CONCLUSIONS: Men with Peyronie's disease are at increased risk of being diagnosed with adverse psychiatric outcomes. Health care providers should ensure that men with Peyronie's disease have a documented mental health status assessment.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Keyword
- penile induration
- mental disorders
- self-injurious behaviors
- cohort studies
Publication and Content Type
- ref (subject category)
- art (subject category)
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