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Probing safety of n...
Probing safety of nanoparticles by outlining sea urchin sensing and signaling cascades
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- Alijagic, Andi, 1992- (author)
- Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare “A. Monroy”, Palermo, Italy
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- Pinsino, Annalisa (author)
- Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare “A. Monroy”, Palermo, Italy
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Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare “A Monroy”, Palermo, Italy (creator_code:org_t)
- New York : Academic Press, 2017
- 2017
- English.
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In: Ecotoxicology and Environmental Safety. - New York : Academic Press. - 0147-6513 .- 1090-2414. ; 144, s. 416-421
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Among currently identified issues presenting risks and benefits to human and ocean health, engineered nanoparticles (ENP) represent a priority. Predictions of their economic and social impact appear extraordinary, but their release in the environment at an uncontrollable rate is in striking contrast with the extremely limited number of studies on environmental impact, especially on the marine environment. The sea urchin has a remarkable sensing environmental system whose function and diversity came into focus during the recent years, after sea urchin genome sequencing. The complex immune system may be the basis wherefore sea urchins can adapt to a dynamic environment and survive even in hazardous conditions both in the adult and in the embryonic life. This review is aimed at discussing the literature in nanotoxicological/ecotoxicological studies with a focus on stress and innate immune signaling in sea urchins. In addition, here we introduce our current development of in vitro-driven probes that could be used to dissect ENP aftermaths, suggesting their future use in immune-nanotoxicology.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- Nano-objects
- Nanotoxicity/nanosafety
- Innate immune response
- In vivo and in vitro studies
- Adult sea urchin immune cells
- Embryonic development
Publication and Content Type
- ref (subject category)
- for (subject category)
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