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Adolescent depressi...
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Alaie, ImanKarolinska Institutet,Uppsala universitet,Ramklint: Barn- och ungdomspsykiatri
(author)
Adolescent depression and adult labor market marginalization : a longitudinal cohort study
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2021-06-25
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Springer,2022
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:oru-92683
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-92683URI
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https://doi.org/10.1007/s00787-021-01825-3DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-451344URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:147023486URI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Funding Agencies:Uppsala University Uppsala-Örebro Regional Research Council RFR-738411 RFR-652841 RFR-840891Uppsala County Council's Funds for Clinical Research LUL-713161 LUL-828241 LUL-914571Sven Jerring Foundation Foundation in Memory of Professor Bror Gadelius
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Adolescent depression is linked to adult ill-health and functional impairment, but recent research suggests that individual/contextual factors might account for this association. This study aimed to test whether the clinical heterogeneity of adolescent depression is related to marginalization from the labor market across early to middle adulthood. Data were drawn from the Uppsala Longitudinal Adolescent Depression Study, a community-based cohort initially assessed with structured clinical interviews at age 16-17. The cohort (n = 321 depressed; n = 218 nondepressed) was followed up after 2+ decades through linkage to nationwide population-based registries. Outcomes included consecutive annual data on unemployment, work disability, social welfare recipiency, and a composite marginalization measure, spanning from age 21 to 40. Longitudinal associations were examined using logistic regression analysis in a generalized estimating equations modeling framework. Subsequent depressive episodes and educational attainment in early adulthood were explored as potential pathways. The results showed that adolescent depression was associated with adult marginalization outcomes, but the strength of association varied across depressed subgroups. Adolescents with persistent depressive disorder had higher odds of all outcomes, including the composite marginalization measure (adjusted OR = 2.0, 95% CI = 1.4-2.7, p < 0.001), and this was partially (31%) mediated by subsequent depressive episodes in early adulthood. Exploratory moderation analysis revealed that entry into tertiary education mitigated the association with later marginalization, but only for adolescents with episodic major depression. In conclusion, the risk for future labor market marginalization is elevated among depressed adolescents, particularly those presenting with persistent depressive disorder. Targeted interventions seem crucial to mitigate the long-lasting impact of early-onset depression.
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Philipson, Anna,1978-Örebro universitet,Institutionen för hälsovetenskaper,University Health Care Research Center, Faculty of Medicine and Health, Örebro University, Örebro, Sweden(Swepub:oru)aaps
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Ssegonja, RichardUppsala universitet,Socialmedicin/CHAP,Lung- allergi- och sömnforskning(Swepub:uu)ricss733
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Copeland, William E.Department of Psychiatry, Vermont Center for Children, Youth, and Families, University of Vermont, Burlington, USA
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Ramklint, Mia,DocentUppsala universitet,Ramklint: Barn- och ungdomspsykiatri(Swepub:uu)miaramkl
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Bohman, Hannes,1965-Karolinska Institutet,Uppsala universitet,Ramklint: Barn- och ungdomspsykiatri(Swepub:uu)hanbo757
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Jonsson, Ulf,1974-Karolinska Institutet,Uppsala universitet,Ramklint: Barn- och ungdomspsykiatri,Karolinska Institutet Center of Neurodevelopmental Disorders (KIND), Centre for Psychiatry Research, Department of Women’s and Children’s Health, Karolinska Institutet, and Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden(Swepub:uu)ulfjo703
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Uppsala universitetRamklint: Barn- och ungdomspsykiatri
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In:European Child and Adolescent Psychiatry: Springer31, s. 1799-18131018-88271435-165X
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