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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00010352naa a2200841 4500
001oai:DiVA.org:oru-95277
003SwePub
008211029s2022 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:148240454
009oai:DiVA.org:uu-457614
009oai:lup.lub.lu.se:c2a98b97-9be3-441c-9fbd-00722d5b35c6
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-952772 URI
0247 a https://doi.org/10.1111/bcp.151322 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1482404542 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4576142 URI
0247 a https://lup.lub.lu.se/record/c2a98b97-9be3-441c-9fbd-00722d5b35c62 URI
040 a (SwePub)orud (SwePub)kid (SwePub)uud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Delanaye, Pierreu Department of Nephrology-Dialysis-Transplantation, University of Liège (ULg CHU), CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hopital Universitaire Caremeau, Nimes, France4 aut
2451 0a Performance of creatinine-based equations to estimate glomerular filtration rate with a methodology adapted to the context of drug dosage adjustment
264 c 2021-12-03
264 1b Wiley-Blackwell Publishing Inc.c 2022
338 a print2 rdacarrier
520 a AIM: The Cockcroft-Gault (CG) creatinine-based equation is still used to estimate glomerular filtration rate (eGFR) for drug dosage adjustment. Incorrect eGFR may lead to hazardous over- or underdosing METHODS: In a cross-sectional analysis, CG was validated against measured GFR (mGFR) in 14,804 participants and compared with the Modification-of-Diet-in-Renal-Diseases (MDRD), Chronic-Kidney-Disease-Epidemiology (CKD-EPI), Lund-Malmö-Revised (LMR), and European-Kidney-Function-Consortium (EKFC) equations. Validation focused on bias, imprecision, and accuracy (percentage of estimates within ±30% of mGFR, P30), overall and stratified for mGFR, age, and body mass index at mGFR <60 mL/min, as well as classification in mGFR stages.RESULTS: The CG equation performed worse than the other equations, overall and in mGFR, age and BMI subgroups in terms of bias (systematic overestimation), imprecision and accuracy except for patients ≥65 years where bias and P30 were similar to MDRD and CKD-EPI, but worse than LMR and EKFC. In subjects with mGFR<60 mL/min and at BMI [18.5-25[kg/m2 , all equations performed similarly and for BMI<18.5kg/m2 CG and LMR had the best results though all equations had poor P30-accuracy. At BMI≥25kg/m2 the bias of the CG increased with increasing BMI (+17.2mL/min at BMI≥40kg/m2 ). The four more recent equations also classified mGFR stages better than CG.CONCLUSIONS: The CG equation showed poor ability to estimate GFR overall and in analyses stratified for GFR, age, and BMI. CG was inferior to correctly classify the patients in the mGFR staging compared to more recent creatinine-based equations.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
653 a Chronic kidney disease
653 a drug adjustment
653 a glomerular filtration rate
653 a chronic kidney disease
653 a drug adjustment
653 a glomerular filtration rate
7001 a Björk, Jonasu Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)ymed-jbj
7001 a Courbebaisse, Marieu Physiology Department, Georges Pompidou European Hospital, Assistance Publique Hôpitaux de Paris, Paris Descartes University, INSERM U1151-CNRS UMR8253, Paris, France.,Paris Diderot University4 aut
7001 a Couzi, Lionelu CHU de Bordeaux, Nephrologie - Transplantation - Dialyse, Université de Bordeaux, CNRS-UMR 5164 Immuno ConcEpT, France.4 aut
7001 a Ebert, Natalieu Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.,Charité - University Medicine Berlin4 aut
7001 a Eriksen, Björn O.u Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway.4 aut
7001 a Dalton, R Neilu The Wellchild Laboratory, Evelina London Children's Hospital, London, United Kingdom.,Evelina London Children's Healthcare4 aut
7001 a Dubourg, Laurenceu Néphrologie, Dialyse, Hypertension et Exploration Fonctionnelle Rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon, France.,Claude Bernard University Lyon 14 aut
7001 a Gaillard, Francoisu Renal Transplantation Department, Assistance Publique-Hôpitaux de Paris (AP-HP), France,Hôpital Edouard Herriot4 aut
7001 a Garrouste, Cyrilu Department of Nephrology, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.4 aut
7001 a Grubb, Andersu Lund University,Lunds universitet,Cystatin C, njursjukdom, amyloidos och antibiotika,Forskargrupper vid Lunds universitet,Cystatin C, renal disease, amyloidosis and antibiotics,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kkem-agr
7001 a Jacquemont, Lolau Renal Transplantation Department, CHU Nantes, Nantes University, Nantes, France.,University of Nantes4 aut
7001 a Hansson, Magnusu Karolinska Institute,Karolinska Institutet,Function area Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital Huddinge and Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.4 aut
7001 a Kamar, Nassimu Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR -BMT, University Paul Sabatier, Toulouse, France.,Rangueil Hospital4 aut
7001 a Lamb, Edmund J.u Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Canterbury, United Kingdom.4 aut
7001 a Legendre, Christopheu Hôpital Necker, AP-HP & Université Paris Descartes, Paris, France.,Necker-Enfants Malades Hospital4 aut
7001 a Littmann, Karinu Karolinska Institute,Karolinska Institutet,Department of Medicine Huddinge (MedH), Karolinska Institute, Huddinge, Sweden.4 aut
7001 a Mariat, Christopheu Service de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, France.4 aut
7001 a Melsom, Toralfu Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway,Service de Néphrologie, Hémodialyse, Aphérèses et Transplantation Rénale, Hôpital Michallon, CHU Grenoble-Alpes, France.4 aut
7001 a Rostaing, Lionelu Service de Néphrologie, Hémodialyse, Aphérèses et Transplantation Rénale, Hôpital Michallon, CHU Grenoble-Alpes, France,Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Grenoble University Hospital4 aut
7001 a Rule, Andrew D.u Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Mayo Clinic Minnesota4 aut
7001 a Schaeffner, Elkeu Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany,Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Charité - University Medicine Berlin4 aut
7001 a Sundin, Per-Ola,d 1971-u Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Geriatrics, School of Medical Sciences, Örebro University, Örebro, Sweden.4 aut0 (Swepub:oru)pasn
7001 a Berg, Ullau Karolinska Institutet,Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.4 aut
7001 a Åsling-Monemi, Kajsau Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.4 aut
7001 a Selistre, Lucianou Mestrado em Ciências da Saúde -Universidade Caxias do Sul Foundation CAPES, Brazil.,University of Caxias do Sul4 aut
7001 a Åkesson, Annau Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,EPI@LUND,Forskargrupper vid Lunds universitet,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)stat-aas
7001 a Larsson, Andersu Uppsala universitet,Klinisk kemi,Academic Medical Center of University of Amsterdam (AMC)4 aut0 (Swepub:uu)andlarss
7001 a Bökenkamp, Arendu Uppsala University4 aut
7001 a Pottel, Hansu Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.,Catholic University of Leuven4 aut
7001 a Nyman, Ulfu Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Department of Translational Medicine,Faculty of Medicine,Radiology Diagnostics, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)ront-uny
7102 a Department of Nephrology-Dialysis-Transplantation, University of Liège (ULg CHU), CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hopital Universitaire Caremeau, Nimes, Franceb Avdelningen för arbets- och miljömedicin4 org
7730 t British Journal of Clinical Pharmacologyd : Wiley-Blackwell Publishing Inc.g 88:5, s. 2118-2127q 88:5<2118-2127x 0306-5251x 1365-2125
8564 u http://dx.doi.org/10.1111/bcp.15132y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95277
8564 8u https://doi.org/10.1111/bcp.15132
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:148240454
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-457614
8564 8u https://lup.lub.lu.se/record/c2a98b97-9be3-441c-9fbd-00722d5b35c6

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