Search: onr:"swepub:oai:DiVA.org:oru-9716" > Associations betwee...
Fältnamn | Indikatorer | Metadata |
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000 | 04356naa a2200565 4500 | |
001 | oai:DiVA.org:oru-9716 | |
003 | SwePub | |
008 | 100212s2009 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-79790 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-97162 URI |
024 | 7 | a https://doi.org/10.1007/s00394-009-0058-22 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-797902 URI |
040 | a (SwePub)orud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Almon, Ricardo,d 1965-u Örebro universitet,Institutionen för klinisk medicin,AFC4 aut0 (Swepub:oru)roan |
245 | 1 0 | a Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands |
264 | c 2009-10-22 | |
264 | 1 | a Heidelberg, Germany :b Springer,c 2009 |
338 | a print2 rdacarrier | |
520 | a Background: The single nucleotide polymorphism (SNP) LCT -13910 C>T, associated with genetically determined phenotypes of lactase persistence (LP) or non-persistence (LNP), was studied in relation to the metabolic syndrome (MS).AIim of the study: The aim was to determine if milk intake and MS are associated. We applied Mendelian randomization (MR). The SNP, LCT -13910 C>T, with the genotypes LP (TT/CT) and LNP (CC), was taken as a proxy for milk consumption.Methods: A representative sample of adults belonging to the Canary Islands Nutrition Survey (ENCA) in Spain aged 18-75 years (n = 551) was genotyped for the LCT -13910 C>T polymorphism. We used the International Diabetes Federation (IDF) criteria to define MS. RESULTS: 60% of the population was LP and 40% LNP. One hundred seven LP subjects (35.0%) and 53 LNP subjects (25.6%) showed MS (chi (2) = 5.04, p = 0.025). LP subjects showed a significantly higher odds ratio (OR) for MS than LNP subjects computed for the whole population: both the crude OR (1.56; 95% CI 1.06-2.31) and adjusted OR for sex, age, daily energy intake, physical activity and educational level (1.57; 95% CI 1.02-2.43). Adjusted OR for women with LP was 1.93; 95% CI 1.06-3.52.Conclusions: The T allele of the SNP might constitute a nutrigenetic factor increasing the susceptibility of LP subjects, especially women, to develop MS in the Canary Islands. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
653 | a LCT-13910 C > T polymorphism | |
653 | a Metabolic syndrome | |
653 | a Metabolic syndrome | |
653 | a Milk | |
653 | a Mendelian randomization | |
653 | a MEDICINE | |
653 | a MEDICIN | |
653 | a Physiology | |
653 | a Fysiologi | |
653 | a Nutrition | |
653 | a Näringslära | |
653 | a Näringslära | |
653 | a Nutrition | |
700 | 1 | a Alvarez-Leon, Eva E.u Univ Las Palmas Gran Canaria, Fac Hlth Sci, Dept Clin Sci, Canary Isl, Spain; Hosp Insular Gran Canaria, Canarian Hlth Serv, Serv Prevent Med, Canary Isl, Spain4 aut |
700 | 1 | a Engfeldt, Peteru Örebro universitet,Institutionen för klinisk medicin,AFC4 aut0 (Swepub:oru)pet |
700 | 1 | a Serra-Majem, Lluisu Univ Las Palmas Gran Canaria, Fac Hlth Sci, Dept Clin Sci, Canary Isl, Spain; Hosp Insular Gran Canaria, Canarian Hlth Serv, Serv Prevent Med, Canary Isl, Spain4 aut |
700 | 1 | a Magnuson, Andersu Örebro University hospital, Örebro, Sweden,KFC USÖ4 aut |
700 | 1 | a Nilsson, Torbjörn K.u Örebro University hospital, Örebro, Sweden,Department of Clinical Chemistry, Örebro University Hospital4 aut0 (Swepub:umu)toni0049 |
710 | 2 | a Örebro universitetb Institutionen för klinisk medicin4 org |
773 | 0 | t European Journal of Nutritiond Heidelberg, Germany : Springerg 49:3, s. 141-146q 49:3<141-146x 1436-6207x 1436-6215 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-9716 |
856 | 4 8 | u https://doi.org/10.1007/s00394-009-0058-2 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-79790 |
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