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The a' velocity by ...
The a' velocity by tissue-Doppler echocardiography correlates to invasive mean left atrial pressure in patients with normal ejection fraction
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- Johansson, Benny (author)
- Department of Heart-Lung and Clinical Physiology, School of Medical Sciences, Örebro University Hospital, Örebro, Sweden
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- Fengsrud, Espen (author)
- Department of Heart-Lung and Clinical Physiology, School of Medical Sciences, Örebro University Hospital, Örebro, Sweden
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- Lundin, Fredrik (author)
- Centre for statistical Clinical Research, County Council of Värmland, Värmland, Sweden
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- Bojö, Leif (author)
- Department of Clinical Physiology, Central Hospital, Karlstad, Sweden
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- Poçi, Dritan, 1969- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Heart-Lung and Clinical Physiology
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(creator_code:org_t)
- 2022-02-09
- 2022
- English.
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In: Scandinavian Cardiovascular Journal. - : Taylor & Francis. - 1401-7431 .- 1651-2006. ; 56:1, s. 6-12
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Abstract
Subject headings
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- Objectives: To evaluate the correlation of a' velocity by tissue-Doppler measurements with invasively measured mean left atrial pressure in patients with normal ejection fraction.Design: In this retrospective study, we evaluated the septal a', lateral a' and average a' velocity by tissue-Doppler echocardiography, in 125 in-hospital patients, 1-12 h before an elective pulmonary vein isolation due to intermittent atrial fibrillation, and compared to invasively measured mean left atrial pressure (LAP) during the invasive procedure. The patients, aged 35-81 years, had to be in sinus rhythm at both examinations, no atrial fibrillation during two procedures, no or mild valve disease and normal ejection fraction (>50%).Results: Invasively measured mean LAP correlated well to septal a' (r = -0.435), lateral a' (r = -0.473) and average a' velocity (r = -0.491). Normal mean LAP (<= 12 mmHg) was found in 95 patients and elevated mean LAP (>12 mmHg) in 30 patients. The patients with elevated mean LAP had a lower septal a' velocity (6.5 +/- 2.7 vs 8.6 +/- 2.3 cm/s; p < .01), lateral a' velocity (5.9 +/- 2.3 vs 8.6 +/- 2.1 cm/s; p < .01) and average a' velocity (6.2 +/- 2.4 vs 8.8 +/- 2.1 cm/s; p < .01) compared to patients with normal mean LAP. Septal a', lateral a' and average a' velocity were good predictors of elevated mean LAP with AUC of 0.78, 0.83 and 0.82. Average a' velocity with cut-off < 7.25 cm/s had a sensitivity of 83% and a specificity of 77% to predict elevated mean LAP.Conclusion: The a' velocity is a good indicator of mean LAP and might be considered in the evaluation of left ventricle filling pressure in patients with normal ejection fraction.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Left ventricular diastolic function
- heart failure with preserved ejection fraction
- invasive left atrial pressure
- left atrial contraction velocity
- echocardiography
- tissue-Doppler
Publication and Content Type
- ref (subject category)
- art (subject category)
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