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The European response to control and manage multi- and extensively drug-resistant Neisseria gonorrhoeae

Cole, Michelle J. (author)
UK Health Security Agency, London, United Kingdom
Day, Michaela (author)
UK Health Security Agency, London, United Kingdom
Jacobsson, Susanne, 1974- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,World Health Organization Collaborating Centre for Gonorrhoea and other STIs
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Amato-Gauci, Andrew J. (author)
European Centre for Disease Prevention and Control, Stockholm, Sweden
Spiteri, Gianfranco (author)
European Centre for Disease Prevention and Control, Stockholm, Sweden
Unemo, Magnus, 1970- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,University College London (UCL), London, United Kingdom; World Health Organization Collaborating Centre for Gonorrhoea and other STIs, Örebro University, Örebro, Sweden
European Gonorrhoea Response Plan Group, - (contributor)
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 (creator_code:org_t)
European Centre for Disease Prevention and Control, 2022
English.
In: Eurosurveillance. - : European Centre for Disease Prevention and Control. - 1025-496X .- 1560-7917. ; 27:18, s. 37-43
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Because cefixime and ceftriaxone resistance in Neisseria gonorrhoeae and gonorrhoea treatment failures were increasing, a response plan to control and manage multidrug-resistant N. gonorrhoeae (MDR-NG) in Europe was published in 2012. The three main areas of the plan were to: (i) strengthen surveillance of antimicrobial resistance (AMR), (ii) implement monitoring of treatment failures and (iii) establish a communication strategy to increase awareness and disseminate AMR results. Since 2012, several additional extensively drug-resistant N. gonorrhoeae (XDR-NG) strains have emerged, and strains with high-level ceftriaxone resistance spread internationally. This prompted an evaluation and review of the 2012 European Centre for Disease Prevention and Control (ECDC) response plan, revealing an overall improvement in many aspects of monitoring AMR in N. gonorrhoeae; however, treatment failure monitoring was a weakness. Accordingly, the plan was updated in 2019 to further support European Union/European Economic Area (EU/EEA) countries in controlling and managing the threat of MDR/XDR-NG in Europe through further strengthening of AMR surveillance and clinical management including treatment failure monitoring. The plan will be assessed biennially to ensure its effectiveness and its value. Along with prevention, diagnostic, treatment and epidemiological surveillance strategies, AMR surveillance is essential for effective control of gonorrhoea.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

Keyword

EU/EEA
MDR-NG
XDR-NG
antimicrobial resistance
cephalosporins
gonorrhoea
surveillance
treatment failure

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art (subject category)

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