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A concise review on...
A concise review on the role of natural and synthetically derived peptides involved in colorectal cancer
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- Das, Alakesh (author)
- Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, India,Chettinad Acad Res & Educ, India
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- Deka, Dikshita (author)
- Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, India,Chettinad Acad Res & Educ, India
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- Banerjee, Antara (author)
- Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, India,Chettinad Acad Res & Educ, India
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- Radhakrishnan, Arun Kumar (author)
- Department of Pharmacology, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, India,Chettinad Acad Res & Educ, India
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- Zhang, Hong, 1957- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Orebro Univ, Sweden
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- Sun, Xiao-Feng (author)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Onkologiska kliniken US
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- Pathak, Surajit (author)
- Department of Medical Biotechnology, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Kelambakkam, Chennai, India,Chettinad Acad Res & Educ, India
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(creator_code:org_t)
- Bentham Science Publishers, 2022
- 2022
- English.
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In: Current Topics in Medicinal Chemistry. - : Bentham Science Publishers. - 1568-0266 .- 1873-4294. ; 22:31, s. 2571-2588
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Colorectal cancer being the second leading cause of cancer-associated deaths, it has become a significant health concern around the globe. Though there are various counts of cancer treatment approaches, many of them show adverse effects and further compromise the condition of the cancer patients. Hence, significant exertions are conducted for the evolution of a novel biological therapeutic approach with better efficacy and minimal side effects. Current research suggests that the application of peptides in colorectal cancer therapeutics holds the possibility of a emerging anticancer reagent. The primary beneficial factors of peptides are their comparatively rapid and easy process of synthesis and the enormous potential for chemical alterations that can be evaluated for designing novel peptides and enhancing the delivery capacity of peptides. Peptides might be utilized as agents with cytotoxic activities or as a carrier of a specific drug or cytotoxic agents that can efficiently target the tumor cells. Further, peptides can also be used as a tool for diagnostic purposes. The recent analysis aims at developing peptides that have the potential to efficiently target the tumor moieties without harming the nearby normal cells. Additionally, decreasing the adverse effects, and unfolding the other therapeutic properties of potential peptides, are also the subject matter of in-depth analysis. This review provides a concise summary of the function of both natural and synthetically derived peptides in colorectal cancer therapeutics that are recently being evaluated and their potent applications in the clinical field.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)
Keyword
- Anti-cancer peptides.
- Colorectal cancer
- Endocrine Gland
- Natural peptides
- Synthetic peptides
- Therapeutics
Publication and Content Type
- ref (subject category)
- for (subject category)
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