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Integration of a dr...
Integration of a droplet-based microfluidic system and silicon nanoribbon FET sensor
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- Afrasiabi, Roodabeh (author)
- KTH,Material- och nanofysik
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- Söderberg, Lovisa M. (author)
- KTH,Proteomik och nanobioteknologi
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- Jönsson, Håkan, PhD, 1979- (author)
- KTH,Proteomik och nanobioteknologi
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- Björk, Per (author)
- RISE,Acreo,Acreo Swedish ICT AB, SE-164 40 Kista, Sweden
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- Svahn Andersson, Helene (author)
- KTH,Proteomik och nanobioteknologi
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- Linnros, Jan, 1953- (author)
- KTH,Material- och nanofysik
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(creator_code:org_t)
- 2016-08-05
- 2016
- English.
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In: Micromachines. - : MDPI AG. - 2072-666X. ; 7:8
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Abstract
Subject headings
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- We present a novel microfluidic system that integrates droplet microfluidics with a silicon nanoribbon field-effect transistor (SiNR FET), and utilize this integrated system to sense differences in pH. The device allows for selective droplet transfer to a continuous water phase, actuated by dielectrophoresis, and subsequent detection of the pH level in the retrieved droplets by SiNR FETs on an electrical sensor chip. The integrated microfluidic system demonstrates a label-free detection method for droplet microfluidics, presenting an alternative to optical fluorescence detection. In this work, we were able to differentiate between droplet trains of one pH-unit difference. The pH-based detection method in our integrated system has the potential to be utilized in the detection of biochemical reactions that induce a pH-shift in the droplets.
Subject headings
- NATURVETENSKAP -- Data- och informationsvetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Nanoteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Nano-technology (hsv//eng)
Keyword
- Droplet microfluidics
- NanoFET
- PH measurement
- Silicon nanoribbon
- Drops
- Electrophoresis
- Field effect transistors
- Fluidic devices
- Integrated control
- Nanoribbons
- Silicon
- Biochemical reactions
- Droplet-based microfluidics
- Integrated microfluidic systems
- Label-free detection method
- PH measurements
- Microfluidics
- Informations- och kommunikationsteknik
Publication and Content Type
- ref (subject category)
- art (subject category)
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