Effects of lung tissue characterization in radiotherapy of breast cancer under deep inspiration breath hold when using Monte Carlo dosimetry

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:DiVA.org:ri-56926" > Effects of lung tis...

1 of 1
Previous record
Next record
To hitlist

LIBRIS Formathandbok (Information om MARC21)

Details
MARC

Fältnamn	Indikatorer	Metadata
000		05706naa a2200757 4500
001		oai:DiVA.org:ri-56926
003		SwePub
008		211122s2021 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:gup.ub.gu.se/310618
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-569262 URI
024	7	a https://doi.org/10.1016/j.ejmp.2021.09.0092 DOI
024	7	a https://gup.ub.gu.se/publication/3106182 URI
040		a (SwePub)rid (SwePub)gu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Andersson, Patriku Gothenburg University,Göteborgs universitet,RISE,University of Gothenburg, Sweden,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology4 aut0 (Swepub:ri)patrik.andersson@ri.se
245	1 0	a Effects of lung tissue characterization in radiotherapy of breast cancer under deep inspiration breath hold when using Monte Carlo dosimetry
264	1	b Associazione Italiana di Fisica Medica,c 2021
338		a print2 rdacarrier
500		a Funding details: Västra Götalandsregionen; Funding details: Strålsäkerhetsmyndigheten, SSM; Funding text 1: Financial support of King Gustav the V Jubilee Clinic Foundation, The Swedish Radiation Safety Authority and The Healthcare Committee, Region Västra Götaland are greatly acknowledged.
520		a Purpose: To investigate the sensitivity of Monte Carlo (MC) calculated lung dose distributions to lung tissue characterization in external beam radiotherapy of breast cancer under Deep Inspiration Breath Hold (DIBH). Methods: EGSnrc based MC software was employed. Mean lung densities for one hundred patients were analysed. CT number frequency and clinical dose distributions were calculated for 15 patients with mean lung density below 0.14 g/cm3. Lung volume with a pre-defined CT numbers was also considered. Lung tissue was characterized by applying different CT calibrations in the low-density region and air-lung tissue thresholds. Dose impact was estimated by Dose Volume Histogram (DVH) parameters. Results: Mean lung densities below 0.14 g/cm3 were found in 10% of the patients. CT numbers below −960 HU dominated the CT frequency distributions with a high rate of CT numbers at −990 HU. Mass density conversion approach influenced the DVH shape. V4Gy and V8Gy varied by 7% and 5% for the selected patients and by 9% and 3.5% for the pre-defined lung volume. V16Gy and V20Gy, were within 2.5%. Regions above 20 Gy were affected. Variations in air- lung tissue differentiation resulted in DVH parameters within 1%. Threshold at −990 HU was confirmed by the CT number frequency distributions. Conclusions: Lung dose distributions were more sensitive to variations in the CT calibration curve below lung (inhale) density than to air-lung tissue differentiation. Low dose regions were mostly affected. The dosimetry effects were found to be potentially important to 10% of the patients treated under DIBH.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng
653		a Absorbed dose
653		a Breast cancer radiotherapy
653		a DIBH
653		a Lung tissue characterization
653		a Monte Carlo simulations
653		a Article
653		a breast cancer
653		a breath holding
653		a cancer radiotherapy
653		a computer assisted tomography
653		a deep inspiration breath hold
653		a dose volume histogram
653		a dosimetry
653		a external beam radiotherapy
653		a human
653		a inspiratory capacity
653		a lung parenchyma
653		a lung volume
653		a major clinical study
653		a patient selection
653		a radiation dose distribution
653		a respiratory airflow
653		a tissue characterization
653		a Absorbed dose
653		a Breast cancer radiotherapy
653		a DIBH
653		a Lung tissue characterization
653		a Monte Carlo simulations
700	1	a Pettersson, Niclasu Sahlgrenska University Hospital, Sweden4 aut
700	1	a Lindberg, Andreasu Sahlgrenska University Hospital, Sweden4 aut
700	1	a Swanpalmer, John,d 1958u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för medicinsk strålningsvetenskap,Institute of Clinical Sciences, Department of Medical Radiation Sciences4 aut0 (Swepub:gu)xswajo
700	1	a Chakarova, Roumianau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för medicinsk strålningsvetenskap,Institute of Clinical Sciences, Department of Medical Radiation Sciences4 aut0 (Swepub:gu)xchakr
710	2	a RISEb University of Gothenburg, Sweden4 org
773	0	t Physica medica (Testo stampato)d : Associazione Italiana di Fisica Medicag 90, s. 83-90q 90<83-90x 1120-1797x 1724-191X
856	4	u https://doi.org/10.1016/j.ejmp.2021.09.009y Fulltext
856	4	u http://www.physicamedica.com/article/S1120179721003082/pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-56926
856	4 8	u https://doi.org/10.1016/j.ejmp.2021.09.009
856	4 8	u https://gup.ub.gu.se/publication/310618

Find in a library

Physica medica (Testo stampato) (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Andersson, Patri ...; Pettersson, Nicl ...; Lindberg, Andrea ...; Swanpalmer, John ...; Chakarova, Roumi ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cancer and Oncol ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

Articles in the publication: Physica medica ( ...

By the university: RISE; University of Gothenburg

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se