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Relationship betwee...
Relationship between sensorial and physical characteristics of topical creams : A comparative study on effects of excipients
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- Ali, Abdullah, 1985- (author)
- Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Malmo Univ, Sweden; Malmo Univ, Sweden; Speximo AB, Sweden
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- Skedung, Lisa (author)
- RISE,Material- och ytdesign,RISE Research Institutes of Sweden, Bioeconomy and Health, Perception and Design, Stockholm, Sweden,RISE Res Inst Sweden Bioecon & Hlth, Sweden
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- Burleigh, S (author)
- Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Lund Univ, Sweden
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- Lavant, Eva (author)
- Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces,Malmo Univ, Sweden; Malmo Univ, Sweden
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- Ringstad, L (author)
- RISE,RISE Research Institutes of Sweden, Bioeconomy and Health, Perception and Design, Stockholm, Sweden,RISE Res Inst Sweden Bioecon & Hlth, Sweden
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- Anderson, Chris D, 1949- (author)
- Linköpings universitet,Linköping University,Avdelningen för cellbiologi,Medicinska fakulteten,Region Östergötland, Hudkliniken i Östergötland
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- Wahlgren, M (author)
- Lund University,Lunds universitet,Avdelningen för livsmedel och läkemedel,Institutionen för processteknik och tillämpad biovetenskap,Institutioner vid LTH,Lunds Tekniska Högskola,Division of Food and Pharma,Department of Process and Life Science Engineering,Departments at LTH,Faculty of Engineering, LTH,Lund Univ, Sweden
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- Engblom, Johan, 1965- (author)
- Malmö University,Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces,Malmo Univ, Sweden; Malmo Univ, Sweden
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(creator_code:org_t)
- Elsevier B.V. 2022
- 2022
- English.
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In: International Journal of Pharmaceutics. - : Elsevier B.V.. - 0378-5173 .- 1873-3476. ; 613
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Abstract
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- Rising consumer demands for safer, more natural, and sustainable topical products have led to increased interest in finding alternative excipients, while retaining functionality and cosmetic appeal. Particle-stabilized Pickering creams have emerged as possible alternatives to replace traditional surfactant-stabilized creams and are thus one of the focuses in this study. The aim of this paper was to study relationships between sensorial characteristics and physical properties to understand how different excipients affect these aspects, comparing one starch particle–stabilized and three surfactant-stabilized formulations. A human panel was used to evaluate sensorial perception, while physical properties were deduced by rheology and tactile friction, together with in vivo and ex vivo skin hydration measurements. The results show that sensorial attributes related to the application phase can be predicted with rheology, while afterfeel attributes can be predicted with tactile friction studies. Differences in rheological and sensory properties among surfactant-based creams could mainly be attributed to the type of emollients used, presence of thickeners and surfactant composition. Differences between surfactant-based creams and a Pickering cream were more evident in relation to the afterfeel perception. Presence of starch particles in the residual film on skin results in high tactile friction and low perception of residual coating, stickiness, greasiness, and slipperiness in sensorial afterfeel. © 2021 The Authors
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Annan teknik -- Livsmedelsteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Other Engineering and Technologies -- Food Engineering (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine (hsv//eng)
Keyword
- Modified starch
- Pickering emulsions
- Rheology
- Sensory study
- Surfactant-free formulations
- Tactile friction
- Topical creams
- cosmetic
- emollient agent
- excipient
- friction
- human
- skin
- Cosmetics
- Emollients
- Excipients
- Humans
- Modified starch
- Pickering emulsions
- Rheology
- Sensory study
- Surfactant-free formulations
- Tactile friction
- Topical creams
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Ali, Abdullah, 1 ...
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Skedung, Lisa
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Burleigh, S
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Lavant, Eva
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Ringstad, L
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Anderson, Chris ...
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show more...
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Wahlgren, M
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Engblom, Johan, ...
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- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Other Engineerin ...
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and Food Engineering
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
- Articles in the publication
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International Jo ...
- By the university
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RISE
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Malmö University
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Lund University
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Linköping University