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On the Reactivity o...
On the Reactivity of 2-Methylene-3-quinuclidinone in Water
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- Ringom, Rune (författare)
- Recipharm OT Chemistry AB, Sweden
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- Blizzard, Tim (författare)
- Xpharma Consulting LLC, USA
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- Sandström, Corine (författare)
- SLU, Sweden
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- Svensson, Per H. (författare)
- RISE,Kemiska processer och läkemedel,KTH Royal Institute of Technology, Sweden
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- Hagberg, Lars (författare)
- Aprea Therapeutics AB, Sweden
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(creator_code:org_t)
- The Japan Institute of Heterocyclic Chemistry, 2023
- 2023
- Engelska.
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Ingår i: Heterocycles. - : The Japan Institute of Heterocyclic Chemistry. - 0385-5414 .- 1881-0942. ; 106:2, s. 271-
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- The biologically active Michael acceptor 2-methylene-3-quinuclidinone (MQ) has a unique chemical reactivity and forms several products upon dissolution in water. With the use of X-ray, NMR and LCMS data the structures of two previously incorrectly characterised compounds are rectified. A complex equilibrium in water, containing novel dimeric species of MQ, and its dependence on temperature, pH and concentration is presented.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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