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Macrocyclic Glycohybrid Toolbox Identifies Novel Antiangiogenesis Agents from Zebrafish Assay
- Dasari, Bhanudas (author)
- Jogula, Srinivas (author)
- Borhade, Ramdas (author)
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- Balasubramanian, Sridhar (author)
- Arya, Prabhat (author)
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- (creator_code:org_t)
- 2013-01-18
- 2013
- English.
- In: Organic Letters. - : American Chemical Society (ACS). - 1523-7060 .- 1523-7052. ; 15:3, s. 432-435
- Journal article (other academic/artistic)
Abstract
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- A practical and modular approach to obtain a diverse set of 14-membered macrocyclic compounds from carbohydrates is developed that utilizes functional groups at C-1 and C-5. The evaluation of this toolbox in various zebrafish assays led to the identification of 2.7f as an antianglogenesis agent.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
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- vet (subject category)
- art (subject category)
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- Dasari, Bhanudas
- Jogula, Srinivas
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- Arya, Prabhat
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- NATURAL SCIENCES
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- Organic Letters
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- Södertörn University
- Karolinska Institutet
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