Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low- and Middle-Income Countries

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Chronic Physical Conditions, Multimorbidity, and Mild Cognitive Impairment in Low- and Middle-Income Countries

Koyanagi, Ai (author): Universitat de Barcelona, Fundació Sant Joan de Déu, Barcelona, Spain / Centro de Investigación Biomédica en Red de Salud Mental, Madrid, Spain

Lara, Elvira (author): entro de Investigación Biomédica en Red de Salud Mental, Madrid, Spain / Universidad Autónoma de Madrid, Madrid, Spain

Stubbs, Brendon (author): South London and Maudsley National Health Service Foundation Trust, London, UK / King's College London, London, UK / Anglia Ruskin University, Chelmsford, UK

Carvalho, Andre F (author): Federal University of Ceará, Fortaleza, Brazil

Oh, Hans (author): University of Southern California, Los Angeles, California, USA

Stickley, Andrew (author): Södertörns högskola,SCOHOST (Stockholm Centre for Health and Social Change)

Veronese, Nicola (author): National Relevance and High Specialization Hospital, Genova, Italy / National Research Council, Neuroscience Institute, Aging Branch, Padova, Italy

Vancampfort, Davy (author): Katholieke Universiteit Leuven, Leuven, Belgium

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2018-02-10
2018
English.
In: Journal of The American Geriatrics Society. - : Wiley-Blackwell. - 0002-8614 .- 1532-5415. ; 66:4, s. 721-727

Related links:: https://www.ncbi.nlm...; show more...; http://www.repositor...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

OBJECTIVES: To assess the association between chronic physical conditions and multimorbidity and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs).DESIGN: Nationally representative, cross-sectional, community-based study.SETTING: Six countries that participated in the World Health Organization Study on Global Ageing and Adult Health.PARTICIPANTS: Individuals aged 50 and older (N=32,715; mean age 62.1 ± 15.6; 51.7% female).MEASUREMENTS: The definition of MCI was based on the recommendations of the National Institute on Ageing and Alzheimer's Association. Ten chronic conditions were assessed (angina pectoris, arthritis, asthma, cataract, chronic lung disease, diabetes mellitus, edentulism, hearing problems, hypertension, stroke). Multivariable logistic regression analysis was conducted to assess the association between chronic physical conditions, multimorbidity (≥2 chronic conditions), and MCI.RESULTS: The prevalence of multimorbidity was 49.8% (95% confidence interval (CI)=48.1-51.5%) and of MCI was 15.3% (95% CI=14.4-16.3%). After adjustment for potential confounders, edentulism (odds ratio (OR)=1.24), arthritis (OR=1.24), chronic lung disease (OR=1.29), cataract (OR=1.33), stroke (OR=1.94), hearing problems (OR=2.27), and multimorbidity (OR=1.40) were significantly associated with MCI. There was a gradual increase in the likelihood of MCI (1 condition: OR=1.21, 95% CI=1.03-1.42; ≥4 conditions: OR=2.07, 95% CI=1.70-2.52).CONCLUSION: These results highlight the need to investigate the underlying mechanisms linking chronic conditions and MCI and whether prevention or treatment of chronic conditions or multimorbidity can reduce the onset of cognitive decline and subsequent dementia, especially in LMICs.

Subject headings

SAMHÄLLSVETENSKAP -- Sociologi (hsv//swe)
SOCIAL SCIENCES -- Sociology (hsv//eng)

Keyword

chronic physical conditions
low- and middle-income countries
mild cognitive impairment
multimorbidity

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ref (subject category)
art (subject category)

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By the author/editor: Koyanagi, Ai; Lara, Elvira; Stubbs, Brendon; Carvalho, Andre ...; Oh, Hans; Stickley, Andrew; show more...; Veronese, Nicola; Vancampfort, Dav ...; show less...

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SOCIAL SCIENCES: SOCIAL SCIENCES; and Sociology

Articles in the publication: Journal of The A ...

By the university: Södertörn University

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