Local Influence Analysis in AB–BA Crossover Designs

• The aim of this article is to develop methodology for detecting influential observations in crossover models with random individual effects. Various case-weighted perturbations are performed. We obtain the influence of the perturbations on each parameter estimator and on their dispersion matrices. The obtained results exhibit the possibility to obtain closed-form expressions of the influence using the residuals in mixed linear models. Some graphical tools are also presented.

Subject headings

NATURVETENSKAP  -- Matematik -- Sannolikhetsteori och statistik (hsv//swe)

NATURAL SCIENCES  -- Mathematics -- Probability Theory and Statistics (hsv//eng)

NATURVETENSKAP  -- Matematik (hsv//swe)

NATURAL SCIENCES  -- Mathematics (hsv//eng)

Keyword

explicit maximum likelihood estimate

influential observation

mixed linear model

perturbation scheme

statistical diagnostics

Statistics

statistik

Publication and Content Type

ref (subject category)

art (subject category)