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Failure of total hi...
Failure of total hip implants : metals and metal release in 52 cases
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Jakobsen, Stig S. (author)
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- Liden, Carola (author)
- Karolinska Institutet
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Soballe, Kjeld (author)
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Johansen, Jeanne D. (author)
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Menne, Torkil (author)
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- Lundgren, Lennart (author)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM),Karolinska Institutet, Sweden
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Bregnbak, David (author)
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Moller, Per (author)
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Jellesen, Morten S. (author)
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Thyssen, Jacob P. (author)
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(creator_code:org_t)
- 2014-07-18
- 2014
- English.
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In: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 71:6, s. 319-325
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
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- BackgroundThe pathogenesis of total joint replacement failure is multifactorial. One hypothesis suggests that corrosion and wear of alloys result in metal ion release, which may then cause sensitization and even implant failure, owing to the acquired immune reactivity. ObjectivesTo assess cobalt, nickel and chromium(VI) release from, and the metal composition of, failed metal-on-ethylene total hip replacements. Materials/methodsImplant components from 52 revision cases were evaluated with spot tests for free nickel, cobalt, and chromium (VI) ions. Implant composition was determined with X-ray fluorescence spectroscopy, and information on the reason for revision and complications in relation to surgery was collected from the medical charts when possible (72%). For 10 implants, corrosion was further characterized with scanning electron microscopy. ResultsWe detected cobalt release from three of 38 removed femoral heads and from one of 24 femoral stems. Nickel release was detected from one of 24 femoral stems. No chromium(VI) release was detected. ConclusionsWe found that cobalt and nickel were released from some failed total hip arthroplasties, and corrosion was frequently observed. Metal ions and particles corroded from metal-on-polyethylene may play a role in the complex aetiopathology of implant failure.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- chromium
- cobalt
- metal allergy
- nickel
- spot test
- total joint replacement
Publication and Content Type
- ref (subject category)
- art (subject category)
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Jakobsen, Stig S ...
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Liden, Carola
-
Soballe, Kjeld
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Johansen, Jeanne ...
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Menne, Torkil
-
Lundgren, Lennar ...
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show more...
-
Bregnbak, David
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Moller, Per
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Jellesen, Morten ...
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Thyssen, Jacob P ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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and Environmental Sc ...
- Articles in the publication
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Contact Dermatit ...
- By the university
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Stockholm University
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Karolinska Institutet