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Free Recall Episodi...
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Boraxbekk, Carl-Johan,1980-Umeå universitet,Enheten för demografi och åldrandeforskning (CEDAR)
(author)
Free Recall Episodic Memory Performance Predicts Dementia Ten Years prior to Clinical Diagnosis : Findings from the Betula Longitudinal Study
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Publisher, publication year, extent ...
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2015-05-01
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S. Karger AG,2015
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:su-126419
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-126419URI
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https://doi.org/10.1159/000381535DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101067URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background/Aims: Early dementia diagnosis is a considerable challenge. The present study examined the predictive value of cognitive performance for a future clinical diagnosis of late-onset Alzheimer's disease or vascular dementia in a random population sample. Methods: Cognitive performance was retrospectively compared between three groups of participants from the Betula longitudinal cohort. Group 1 developed dementia 11-22 years after baseline testing (n = 111) and group 2 after 1-10 years (n = 280); group 3 showed no deterioration towards dementia during the study period (n = 2,855). Multinomial logistic regression analysis was used to investigate the predictive value of tests reflecting episodic memory performance, semantic memory performance, visuospatial ability, and prospective memory performance. Results: Age-and education-corrected performance on two free recall episodic memory tests significantly predicted dementia 10 years prior to clinical diagnosis. Free recall performance also predicted dementia 11-22 years prior to diagnosis when controlling for education, but not when age was added to the model. Conclusion: The present results support the suggestion that two free recall-based tests of episodic memory function may be useful for detecting individuals at risk of developing dementia 10 years prior to clinical diagnosis.
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Lundquist, AndersUmeå universitet,Statistik(Swepub:umu)anslst97
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Nordin, AnnelieUmeå universitet,Psykiatri(Swepub:umu)anenon01
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Nyberg, LarsUmeå universitet,Fysiologi,Diagnostisk radiologi(Swepub:umu)lany0001
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Nilsson, Lars-GöranStockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Aging Research Center, Karolinska Institutet
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Adolfsson, RolfUmeå universitet,Psykiatri(Swepub:umu)road0001
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Umeå universitetEnheten för demografi och åldrandeforskning (CEDAR)
(creator_code:org_t)
Related titles
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In:Dementia and Geriatric Cognitive Disorders Extra: S. Karger AG5:2, s. 191-2021664-5464
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