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QNet : an agglomerative method for the construction of phylogenetic networks from weighted quartets.
- Grünewald, Stefan (author)
-
- Forslund, Kristoffer (author)
- Stockholms universitet,Institutionen för biokemi och biofysik,Stockholms Bioinformatikcentrum,Sonnhammer
- Dress, Andreas (author)
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- Moulton, Vincent (author)
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- (creator_code:org_t)
- 2007
- 2007
- English.
- In: Mol Biol Evol. - 0737-4038. ; 24:2, s. 532-8
- Journal article (peer-reviewed)
Abstract
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- We present QNet, a method for constructing split networks from weighted quartet trees. QNet can be viewed as a quartet analogue of the distance-based Neighbor-Net (NNet) method for network construction. Just as NNet, QNet works by agglomeratively computing a collection of circular weighted splits of the taxa set which is subsequently represented by a planar split network. To illustrate the applicability of QNet, we apply it to a previously published Salmonella data set. We conclude that QNet can provide a useful alternative to NNet if distance data are not available or a character-based approach is preferred. Moreover, it can be used as an aid for determining when a quartet-based tree-building method may or may not be appropriate for a given data set. QNet is freely available for download.
Keyword
- Algorithms
- Least-Squares Analysis
- Models; Genetic
- Models; Statistical
- Phylogeny
- Salmonella/genetics
- Software
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- ref (subject category)
- art (subject category)
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