Search: onr:"swepub:oai:DiVA.org:su-160996" >
Self-rated intensit...
Self-rated intensity of habitual physical activities is positively associated with dopamine D-2/3 receptor availability and cognition
-
- Köhncke, Ylva (author)
- Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Max Planck Institute for Human Development, Germany
-
- Papenberg, Goran (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
-
- Jonasson, Lars S., 1983- (author)
- Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för integrativ medicinsk biologi (IMB)
-
show more...
-
Karalija, Nina (author)
-
- Wåhlin, Anders (author)
- Umeå universitet,Radiofysik,Umeå centrum för funktionell hjärnavbildning (UFBI)
-
- Salami, Alireza (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Univ, S-11330 Stockholm, Sweden
-
- Andersson, Micael (author)
- Umeå universitet,Diagnostisk radiologi,Institutionen för integrativ medicinsk biologi (IMB)
-
- Axelsson, Jan, 1966- (author)
- Umeå universitet,Radiofysik,Umeå centrum för funktionell hjärnavbildning (UFBI)
-
- Nyberg, Lars, 1966- (author)
- Umeå universitet,Diagnostisk radiologi,Institutionen för integrativ medicinsk biologi (IMB),Umeå centrum för funktionell hjärnavbildning (UFBI)
-
- Riklund, Katrine (author)
- Umeå universitet,Diagnostisk radiologi,Umeå centrum för funktionell hjärnavbildning (UFBI)
-
- Bäckman, Lars (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
-
Lindenberger, Ulman (author)
-
- Lövden, Martin (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- English.
-
In: NeuroImage. - : Elsevier BV. - 1053-8119 .- 1095-9572. ; 181, s. 605-616
- Related links:
-
https://pure.mpg.de/...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Between-person differences in cognitive performance in older age are associated with variations in physical activity. The neurotransmitter dopamine (DA) contributes to cognitive performance, and the DA system deteriorates with advancing age. Animal data and a patient study suggest that physical activity modulates DA receptor availability, but data from healthy humans are lacking. In a cross-sectional study with 178 adults aged 64-68 years, we investigated links among self-reported physical activity, D(2/3)DA receptor (D2/3DR) availability, and cognitive performance. D2/3DR availability was measured with [C-11]raclopride positron emission tomography at rest. We used structural equation modeling to obtain latent factors for processing speed, episodic memory, working memory, physical activity, and D2/3DR availability in caudate, putamen, and hippocampus. Physical activity intensity was positively associated with D2/3DR availability in caudate, but not putamen and hippocampus. Frequency of physical activity was not related to D2/3DR availability. Physical activity intensity was positively related to episodic memory and working memory. D2/3DR availability in caudate and hippocampus was positively related to episodic memory. Taken together, our results suggest that striatal DA availability might be a neurochemical correlate of episodic memory that is also associated with physical activity.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Cognition
- Episodic memory
- Dopamine
- Physical activity
- Aging
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
NeuroImage
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Köhncke, Ylva
-
Papenberg, Goran
-
Jonasson, Lars S ...
-
Karalija, Nina
-
Wåhlin, Anders
-
Salami, Alireza
-
show more...
-
Andersson, Micae ...
-
Axelsson, Jan, 1 ...
-
Nyberg, Lars, 19 ...
-
Riklund, Katrine
-
Bäckman, Lars
-
Lindenberger, Ul ...
-
Lövden, Martin
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Other Medical an ...
-
and Gerontology spec ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Geriatrics
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
- Articles in the publication
-
NeuroImage
- By the university
-
Stockholm University
-
Umeå University
-
Karolinska Institutet