Syntheses of Haemophilus influenzae typed d and e antigens, each containing a 2-acetamido-2-deoxy-ss-D-mannopyranosyluronic acid residue, and of analogues and derivatives of 3,6-di-O-α-D-mannopyranosyl-α-D-mannopyranoside

• Syntheses ofp-nitrophenyl 2-acetamido-3-0-(2-acetamido-2-deoxy-ß-Dglucopyranosyl)- 2-deoxy-ß-D-mannopyranosiduronic acidand p- -trifiuoroacetamidophenyl2-acetamido-4-0-(2-acetamido-2-deoxy-ß-D- -glucopyranosyl)-2-deoxy-ß-D-mannopyranosiduronic acid that corresponds to the repeating units of Haemophilus influenzae type d and e capsular antigens, are discussed. These were needed for immunological studies. Analogues and derivatives of 3,6-di-O-a-D-mannopyranosyl-oc-D-mannopyranoside were synthesised and the syntheses of these and their potential biological value is discussed.

Subject headings

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Keyword

Organic Chemistry

organisk kemi

Publication and Content Type

vet (subject category)

dok (subject category)