Search: onr:"swepub:oai:DiVA.org:su-175093" >
Mitochondrial DNA a...
Mitochondrial DNA analysis of a Viking age mass grave in Sweden
-
- Bus, Magdalena M. (author)
- Uppsala universitet,Medicinsk genetik och genomik,Science for Life Laboratory, SciLifeLab
-
- Lembring, Maria (author)
- Uppsala universitet,Medicinsk genetik och genomik,Science for Life Laboratory, SciLifeLab
-
- Kjellström, Anna (author)
- Stockholms universitet,Institutionen för arkeologi och antikens kultur,Stockholm Univ, Dept Archaeol & Class Studies, Osteoarchaeol Res Lab, S-10691 Stockholm, Sweden
-
show more...
-
- Strobl, Christina (author)
- Med Univ Innsbruck, Inst Legal Med, A-6020 Innsbruck, Austria
-
- Zimmermann, Bettina (author)
- Med Univ Innsbruck, Inst Legal Med, A-6020 Innsbruck, Austria
-
- Parson, Walther (author)
- Med Univ Innsbruck, Inst Legal Med, A-6020 Innsbruck, Austria;Penn State Univ, Forens Sci Program, University Pk, PA 16802 USA
-
- Allen, Marie (author)
- Uppsala universitet,Medicinsk genetik och genomik,Science for Life Laboratory, SciLifeLab
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2019
- 2019
- English.
-
In: Forensic Science International. - : Elsevier BV. - 1872-4973 .- 1878-0326. ; 42, s. 268-274
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- In 1998, a Viking Age mass grave was discovered and excavated at St. Laurence's churchyard in Sigtuna, Sweden. The excavated bones underwent osteoarchaeological analysis and were assigned to at least 19 individuals. Eleven skeletons showed sharp force trauma from bladed weapons. Mass graves are an unusual finding from this time period, making the burial context extraordinary. To investigate a possible maternal kinship among the individuals, bones and teeth from the skeletal remains were selected for mitochondrial DNA (mtDNA) analysis. Sanger sequencing of short stretches of the hypervariable segments I and II (HVS-I and HVS-II) was performed. A subset of the samples was also analysed by massively parallel sequencing analysis (MPS) of the entire mtDNA genome using the Precision ID mtDNA Whole Genome Panel. A total of 15 unique and three shared mtDNA profiles were obtained. Based on a combination of genetic and archaeological data, we conclude that a minimum of 20 individuals was buried in the mass grave. The majority of the individuals were not maternally related. However, two possible pairs of siblings or mother-child relationships were identified. All individuals were assigned to West Eurasian haplogroups, with a predominance of haplogroup H. Although the remains showed an advanced level of DNA degradation, the combined use of Sanger sequencing and MPS with the Precision ID mtDNA Whole Genome Panel revealed at least partial mtDNA data for all samples.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- HUMANIORA -- Historia och arkeologi (hsv//swe)
- HUMANITIES -- History and Archaeology (hsv//eng)
- HUMANIORA -- Historia och arkeologi -- Arkeologi (hsv//swe)
- HUMANITIES -- History and Archaeology -- Archaeology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Keyword
- Human identification
- Sanger sequencing
- Massively parallel sequencing
- Mitogenome
- Bone samples
- Degradation
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database