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Geographic variatio...
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Keehnen, NaomiStockholms universitet,Avdelningen för populationsgenetik
(author)
Geographic variation in hemocyte diversity and phagocytic propensity shows a diffuse genomic signature in the green veined white butterfly
Publisher, publication year, extent ...
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Cold Spring Harbor Laboratory,2024
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:su-175463
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-175463URI
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https://doi.org/10.1101/790782DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:vet swepub-contenttype
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Subject category:ovr swepub-publicationtype
Notes
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Insects rely on their innate immune system to successfully mediate complex interactions with their internal microbiota, as well as the microbes present in the environment. Given the variation in microbes across habitats, the challenges to respond to them is likely to result in local adaptation in the immune system. Here we focus upon phagocytosis, a mechanism by which pathogens and foreign particles are engulfed in order to be contained, killed and processed for antigen presentation. We investigated the phenotypic and genetic variation related to phagocytosis, in two allopatric populations of the butterfly Pieris napi. We found that the populations differ in their hemocyte composition, and overall phagocytic capability, driven by the increased phagocytic propensity of each cell type. However, no evidence for divergence in phagocytosis-related genes was observed, though an enrichment of genes involved in glutamine metabolism was found, which have recently been linked to immune cell differentiation in mammals.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Fors, LisaStockholms universitet,Avdelningen för populationsgenetik(Swepub:su)lifo6373
(author)
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Järver, PeterStockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut(Swepub:su)pjr
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Spetz, Anna-LenaStockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut(Swepub:su)aspet
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Nylin, SörenStockholms universitet,Avdelningen för zoologisk ekologi(Swepub:su)snylin
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Theopold, UlrichStockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut(Swepub:su)utheo
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Wheat, ChristopherStockholms universitet,Avdelningen för populationsgenetik(Swepub:su)cwhea
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Stockholms universitetAvdelningen för populationsgenetik
(creator_code:org_t)
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