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Advancing Solutions...
Advancing Solutions to the Carbohydrate Sequencing Challenge
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Gray, Christopher J. (author)
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Migas, Lukasz G. (author)
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Barran, Perdita E. (author)
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Pagel, Kevin (author)
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Seeberger, Peter H. (author)
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Eyers, Claire E. (author)
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Boons, Geert-Jan (author)
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Pohl, Nicola L. B. (author)
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Compagnon, Isabelle (author)
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- Widmalm, Göran (author)
- Stockholms universitet,Institutionen för organisk kemi
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Flitsch, Sabine L. (author)
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(creator_code:org_t)
- 2019-08-12
- 2019
- English.
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In: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 0002-7863 .- 1520-5126. ; 141:37, s. 14463-14479
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https://hal-univ-lyo...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Carbohydrates possess a variety of distinct features with stereochemistry playing a particularly important role in distinguishing their structure and function. Monosaccharide building blocks are defined by a high density of chiral centers. Additionally, the anomericity and regiochemistry of the glycosidic linkages carry important biological information. Any carbohydrate-sequencing method needs to be precise in determining all aspects of this stereodiversity. Recently, several advances have been made in developing fast and precise analytical techniques that have the potential to address the stereochemical complexity of carbohydrates. This perspective seeks to provide an overview of some of these emerging techniques, focusing on those that are based on NMR and MS-hybridized technologies including ion mobility spectrometry and IR spectroscopy.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
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- ref (subject category)
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- By the author/editor
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Gray, Christophe ...
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Migas, Lukasz G.
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Barran, Perdita ...
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Pagel, Kevin
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Seeberger, Peter ...
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Eyers, Claire E.
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show more...
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Boons, Geert-Jan
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Pohl, Nicola L. ...
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Compagnon, Isabe ...
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Widmalm, Göran
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Flitsch, Sabine ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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Journal of the A ...
- By the university
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Stockholm University