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The Quest for Ortho...
The Quest for Orthologs benchmark service and consensus calls in 2020
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Altenhoff, Adrian M. (author)
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Garrayo-Ventas, Javier (author)
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Cosentino, Salvatore (author)
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Emms, David (author)
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Glover, Natasha M. (author)
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Hernández-Plaza, Ana (author)
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Nevers, Yannis (author)
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Sundesha, Vicky (author)
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Szklarczyk, Damian (author)
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Fernández, José M. (author)
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Codó, Laia (author)
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Li Gelpi, Josep (author)
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Huerta-Cepas, Jaime (author)
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Iwasaki, Wataru (author)
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Kelly, Steven (author)
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Lecompte, Odile (author)
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Muffato, Matthieu (author)
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Martin, Maria J. (author)
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Capella-Gutierrez, Salvador (author)
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Thomas, Paul D. (author)
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- Sonnhammer, Erik (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för biokemi och biofysik
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Dessimoz, Christophe (author)
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(creator_code:org_t)
- 2020-05-06
- 2020
- English.
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In: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 48:W1, s. W538-W545
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Abstract
Subject headings
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- The identification of orthologs-genes in different species which descended from the same gene in their last common ancestor-is a prerequisite for many analyses in comparative genomics and molecular evolution. Numerous algorithms and resources have been conceived to address this problem, but benchmarking and interpreting them is fraught with difficulties (need to compare them on a common input dataset, absence of ground truth, computational cost of calling orthologs). To address this, the Quest for Orthologs consortium maintains a reference set of proteomes and provides a web server for continuous orthology benchmarking (http://orthology.benchmarkservice.org). Furthermore, consensus ortholog calls derived from public benchmark submissions are provided on the Alliance of Genome Resources website, the joint portal of NIH-funded model organism databases.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Altenhoff, Adria ...
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Garrayo-Ventas, ...
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Cosentino, Salva ...
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Emms, David
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Glover, Natasha ...
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Hernández-Plaza, ...
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show more...
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Nevers, Yannis
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Sundesha, Vicky
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Szklarczyk, Dami ...
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Fernández, José ...
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Codó, Laia
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Li Gelpi, Josep
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Huerta-Cepas, Ja ...
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Iwasaki, Wataru
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Kelly, Steven
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Lecompte, Odile
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Muffato, Matthie ...
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Martin, Maria J.
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Capella-Gutierre ...
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Thomas, Paul D.
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Sonnhammer, Erik
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Dessimoz, Christ ...
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
- Articles in the publication
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Nucleic Acids Re ...
- By the university
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Stockholm University