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Cortical thickness ...
Cortical thickness and resting-state cardiac function across the lifespan : A cross-sectional pooled mega-analysis
- Article/chapterEnglish2021
Publisher, publication year, extent ...
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2020-10-10
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Wiley,2021
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:su-195353
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-195353URI
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https://doi.org/10.1111/psyp.13688DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:144894170URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5% female), mean age 36.7 years (range: 12–87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS—or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Abler, Birgit
(author)
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Agartz, IngridKarolinska Institutet
(author)
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Åkerstedt, TorbjörnStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Stockholm, Sweden(Swepub:su)tke
(author)
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Andreassen, Ole A.
(author)
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Anthony, Mia
(author)
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Bär, Karl-Jürgen
(author)
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Bertsch, Katja
(author)
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Brown, Rebecca C.
(author)
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Brunner, Romuald
(author)
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Carnevali, Luca
(author)
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Critchley, Hugo D.
(author)
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Cullen, Kathryn R.
(author)
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de Geus, Eco J. C.
(author)
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Dziobek, Isabel
(author)
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Ferger, Marc D.
(author)
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Fischer, HåkanStockholms universitet,Biologisk psykologi(Swepub:su)hkfi4392
(author)
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Flor, Herta
(author)
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Gaebler, Michael
(author)
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Gianaros, Peter J.
(author)
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Giummarra, Melita J.
(author)
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Greening, Steven G.
(author)
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Guendelman, Simon
(author)
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Heathers, James A. J.
(author)
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Herpertz, Sabine C.
(author)
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Hu, Mandy X.
(author)
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Jentschke, Sebastian
(author)
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Kaess, Michael
(author)
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Kaufmann, TobiasKarolinska Institutet
(author)
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Klimes-Dougan, Bonnie
(author)
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Koelsch, Stefan
(author)
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Krauch, Marlene
(author)
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Kumral, Deniz
(author)
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Lamers, Femke
(author)
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Lee, Tae-Ho
(author)
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Lekander, MatsStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Stockholm, Sweden(Swepub:su)mleka
(author)
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Lin, Feng
(author)
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Lotze, Martin
(author)
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Makovac, Elena
(author)
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Mancini, Matteo
(author)
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Mancke, Falk
(author)
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Månsson, Kristoffer N.T.Stockholms universitet,Klinisk psykologi,Karolinska Institutet, Stockholm County Council(Swepub:su)kmn
(author)
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Manuck, Stephen B.
(author)
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Mather, Mara
(author)
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Meeten, Frances
(author)
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Min, Jungwon
(author)
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Mueller, Bryon
(author)
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Muench, Vera
(author)
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Nees, Frauke
(author)
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Nga, Lin
(author)
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Nilsonne, GustavStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Stockholm, Sweden(Swepub:su)guni6529
(author)
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Ordonez Acuna, Daniela
(author)
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Osnes, Berge
(author)
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Ottaviani, Cristina
(author)
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Penninx, Brenda W. J. H.
(author)
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Ponzio, Allison
(author)
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Poudel, Govinda R.
(author)
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Reinelt, Janis
(author)
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Ren, Ping
(author)
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Sakaki, Michiko
(author)
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Schumann, Andy
(author)
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Sørensen, Lin
(author)
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Specht, Karsten
(author)
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Straub, Joana
(author)
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Tamm, SandraStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Stockholm, Sweden: Oxford University, Oxford, UK(Swepub:su)sata4198
(author)
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Thai, Michelle
(author)
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Thayer, Julian F.
(author)
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Ubani, Benjamin
(author)
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van der Mee, Denise J.
(author)
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van Velzen, Laura S.
(author)
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Ventura-Bort, Carlos
(author)
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Villringer, Arno
(author)
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Watson, David R.
(author)
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Wei, Luqing
(author)
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Wendt, Julia
(author)
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Westlund Schreiner, Melinda
(author)
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Westlye, Lars T.
(author)
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Weymar, Mathias
(author)
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Winkelmann, Tobias
(author)
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Wu, Guo-Rong
(author)
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Yoo, Hyun Joo
(author)
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Quintana, Daniel S.
(author)
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de la Cruz, F
(author)
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Karolinska InstitutetStressforskningsinstitutet
(creator_code:org_t)
Related titles
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In:Psychophysiology: Wiley58:70048-57721469-89861540-5958
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- By the author/editor
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Koenig, Julian
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Abler, Birgit
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Agartz, Ingrid
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Åkerstedt, Torbj ...
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Andreassen, Ole ...
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Anthony, Mia
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show more...
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Bär, Karl-Jürgen
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Bertsch, Katja
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Brown, Rebecca C ...
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Brunner, Romuald
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Carnevali, Luca
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Critchley, Hugo ...
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Cullen, Kathryn ...
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de Geus, Eco J. ...
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Dziobek, Isabel
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Ferger, Marc D.
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Fischer, Håkan
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Flor, Herta
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Gaebler, Michael
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Gianaros, Peter ...
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Giummarra, Melit ...
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Greening, Steven ...
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Guendelman, Simo ...
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Heathers, James ...
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Herpertz, Sabine ...
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Hu, Mandy X.
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Jentschke, Sebas ...
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Kaess, Michael
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Kaufmann, Tobias
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Klimes-Dougan, B ...
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Koelsch, Stefan
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Krauch, Marlene
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Kumral, Deniz
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Lamers, Femke
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Lee, Tae-Ho
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Lekander, Mats
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Lin, Feng
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Lotze, Martin
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Makovac, Elena
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Mancini, Matteo
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Mancke, Falk
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Månsson, Kristof ...
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Manuck, Stephen ...
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Mather, Mara
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Meeten, Frances
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Min, Jungwon
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Mueller, Bryon
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Muench, Vera
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Nees, Frauke
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Nga, Lin
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Nilsonne, Gustav
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Ordonez Acuna, D ...
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Osnes, Berge
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Ottaviani, Crist ...
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Penninx, Brenda ...
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Ponzio, Allison
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Poudel, Govinda ...
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Reinelt, Janis
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Ren, Ping
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Sakaki, Michiko
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Schumann, Andy
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Sørensen, Lin
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Specht, Karsten
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Straub, Joana
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Tamm, Sandra
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Thai, Michelle
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Thayer, Julian F ...
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Ubani, Benjamin
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van der Mee, Den ...
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van Velzen, Laur ...
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Ventura-Bort, Ca ...
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Villringer, Arno
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Watson, David R.
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Wei, Luqing
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Wendt, Julia
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Westlund Schrein ...
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Westlye, Lars T.
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Weymar, Mathias
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Winkelmann, Tobi ...
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Wu, Guo-Rong
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Yoo, Hyun Joo
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Quintana, Daniel ...
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de la Cruz, F
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- About the subject
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
- Articles in the publication
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Psychophysiology
- By the university
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Stockholm University
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Karolinska Institutet