Search: onr:"swepub:oai:DiVA.org:su-195563" >
Recent Smell Loss I...
-
Gerkin, Richard C.
(author)
Recent Smell Loss Is the Best Predictor of COVID-19 Among Individuals With Recent Respiratory Symptoms
- Article/chapterEnglish2021
Publisher, publication year, extent ...
-
2020-12-25
-
Oxford University Press (OUP),2021
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:su-195563
-
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-195563URI
-
https://doi.org/10.1093/chemse/bjaa081DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:149039254URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
In a preregistered, cross-sectional study, we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0–100 visual analog scales (VAS) for participants reporting a positive (C19+; n = 4148) or negative (C19−; n = 546) COVID-19 laboratory test outcome. Logistic regression models identified univariate and multivariate predictors of COVID-19 status and post-COVID-19 olfactory recovery. Both C19+ and C19− groups exhibited smell loss, but it was significantly larger in C19+ participants (mean ± SD, C19+: −82.5 ± 27.2 points; C19−: −59.8 ± 37.7). Smell loss during illness was the best predictor of COVID-19 in both univariate and multivariate models (ROC AUC = 0.72). Additional variables provide negligible model improvement. VAS ratings of smell loss were more predictive than binary chemosensory yes/no-questions or other cardinal symptoms (e.g., fever). Olfactory recovery within 40 days of respiratory symptom onset was reported for ~50% of participants and was best predicted by time since respiratory symptom onset. We find that quantified smell loss is the best predictor of COVID-19 amongst those with symptoms of respiratory illness. To aid clinicians and contact tracers in identifying individuals with a high likelihood of having COVID-19, we propose a novel 0–10 scale to screen for recent olfactory loss, the ODoR-19. We find that numeric ratings ≤2 indicate high odds of symptomatic COVID-19 (4 < OR < 10). Once independently validated, this tool could be deployed when viral lab tests are impractical or unavailable.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Ohla, Kathrin
(author)
-
Veldhuizen, Maria G.
(author)
-
Joseph, Paule
(author)
-
Kelly, Christine E.
(author)
-
Bakke, Alyssa J.
(author)
-
Steele, Kimberley E.
(author)
-
Farruggia, Michael C.
(author)
-
Pellegrino, Robert
(author)
-
Pepino, Marta Y.
(author)
-
Bouysset, Cedric
(author)
-
Soler, Graciela M.
(author)
-
Pereda-Loth, Veronica
(author)
-
Dibattista, Michele
(author)
-
Cooper, Keiland W.
(author)
-
Croijmans, Ilja
(author)
-
Di Pizio, Antonella
(author)
-
Ozdener, Mehmet Hakan
(author)
-
Fjaeldstad, Alexander W.
(author)
-
Lin, Cailu
(author)
-
Sandell, Mari A.
(author)
-
Singh, Preet B.
(author)
-
Brindha, V. Evelyn
(author)
-
Olsson, Shannon B.
(author)
-
Saraiva, Luis R.
(author)
-
Ahuja, Gaurav
(author)
-
Alwashahi, Mohammed K.
(author)
-
Bhutani, Surabhi
(author)
-
D'Errico, Anna
(author)
-
Fornazieri, Marco A.
(author)
-
Golebiowski, Jerome
(author)
-
Hwang, Liang Dar
(author)
-
Ozturk, Lina
(author)
-
Roura, Eugeni
(author)
-
Spinelli, Sara
(author)
-
Whitcroft, Katherine L.
(author)
-
Faraji, Farhoud
(author)
-
Fischmeister, Florian Ph S.
(author)
-
Heinbockel, Thomas
(author)
-
Hsieh, Julien W.
(author)
-
Huart, Caroline
(author)
-
Konstantinidis, Iordanis
(author)
-
Menini, Anna
(author)
-
Morini, Gabriella
(author)
-
Olofsson, Jonas K.,1978-Stockholms universitet,Psykologiska institutionen(Swepub:su)jool8931
(author)
-
Philpott, Carl M.
(author)
-
Pierron, Denis
(author)
-
Shields, Vonnie D. C.
(author)
-
Voznessenskaya, Vera V.
(author)
-
Albayay, Javier
(author)
-
Altundag, Aytug
(author)
-
Bensafi, Moustafa
(author)
-
Bock, Maria Adelaida
(author)
-
Calcinoni, Orietta
(author)
-
Fredborg, WilliamStockholms universitet,Psykologiska institutionen(Swepub:su)wifr5556
(author)
-
Laudamiel, Christophe
(author)
-
Lim, Juyun
(author)
-
Lundstrom, Johan N.Karolinska Institutet
(author)
-
Macchi, Alberto
(author)
-
Meyer, Pablo
(author)
-
Moein, Shima T.
(author)
-
Santamaria, Enrique
(author)
-
Sengupta, Debarka
(author)
-
Dominguez, Paloma Rohlfs
(author)
-
Yanik, Huseyin
(author)
-
Hummel, Thomas
(author)
-
Hayes, John E.
(author)
-
Reed, Danielle R.
(author)
-
Niv, Masha Y.
(author)
-
Munger, Steven D.
(author)
-
Parma, Valentina
(author)
-
Stockholms universitetPsykologiska institutionen
(creator_code:org_t)
Related titles
-
In:Chemical Senses: Oxford University Press (OUP)460379-864X1464-3553
Internet link
Find in a library
To the university's database
- By the author/editor
-
Gerkin, Richard ...
-
Ohla, Kathrin
-
Veldhuizen, Mari ...
-
Joseph, Paule
-
Kelly, Christine ...
-
Bakke, Alyssa J.
-
show more...
-
Steele, Kimberle ...
-
Farruggia, Micha ...
-
Pellegrino, Robe ...
-
Pepino, Marta Y.
-
Bouysset, Cedric
-
Soler, Graciela ...
-
Pereda-Loth, Ver ...
-
Dibattista, Mich ...
-
Cooper, Keiland ...
-
Croijmans, Ilja
-
Di Pizio, Antone ...
-
Ozdener, Mehmet ...
-
Fjaeldstad, Alex ...
-
Lin, Cailu
-
Sandell, Mari A.
-
Singh, Preet B.
-
Brindha, V. Evel ...
-
Olsson, Shannon ...
-
Saraiva, Luis R.
-
Ahuja, Gaurav
-
Alwashahi, Moham ...
-
Bhutani, Surabhi
-
D'Errico, Anna
-
Fornazieri, Marc ...
-
Golebiowski, Jer ...
-
Hwang, Liang Dar
-
Ozturk, Lina
-
Roura, Eugeni
-
Spinelli, Sara
-
Whitcroft, Kathe ...
-
Faraji, Farhoud
-
Fischmeister, Fl ...
-
Heinbockel, Thom ...
-
Hsieh, Julien W.
-
Huart, Caroline
-
Konstantinidis, ...
-
Menini, Anna
-
Morini, Gabriell ...
-
Olofsson, Jonas ...
-
Philpott, Carl M ...
-
Pierron, Denis
-
Shields, Vonnie ...
-
Voznessenskaya, ...
-
Albayay, Javier
-
Altundag, Aytug
-
Bensafi, Moustaf ...
-
Bock, Maria Adel ...
-
Calcinoni, Oriet ...
-
Fredborg, Willia ...
-
Laudamiel, Chris ...
-
Lim, Juyun
-
Lundstrom, Johan ...
-
Macchi, Alberto
-
Meyer, Pablo
-
Moein, Shima T.
-
Santamaria, Enri ...
-
Sengupta, Debark ...
-
Dominguez, Palom ...
-
Yanik, Huseyin
-
Hummel, Thomas
-
Hayes, John E.
-
Reed, Danielle R ...
-
Niv, Masha Y.
-
Munger, Steven D ...
-
Parma, Valentina
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
- Articles in the publication
-
Chemical Senses
- By the university
-
Stockholm University
-
Karolinska Institutet