Search: onr:"swepub:oai:DiVA.org:su-204939" >
Macromolecular Vira...
Macromolecular Viral Entry Inhibitors as Broad-Spectrum First-Line Antivirals with Activity against SARS-CoV-2
- Article/chapterEnglish2022
Publisher, publication year, extent ...
-
2022-05-11
-
Wiley,2022
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:su-204939
-
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-204939URI
-
https://doi.org/10.1002/advs.202201378DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS-CoV-2. Macromolecular inhibitors are shown to exhibit the highly sought-after broad-spectrum antiviral activity, which covers most analyzed enveloped viruses and all of the variants of concern for SARS-CoV-2 tested. The inhibitory activity is quantified in vitro in appropriate cell culture models and for respiratory viral pathogens (respiratory syncytial virus and SARS-CoV-2) in mice. Results of this study comprise a significant step along the translational path of macromolecular inhibitors of virus cell entry, specifically against enveloped respiratory viruses.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Dias Loiola, Lívia Mesquita
(author)
-
Issmail, Leila
(author)
-
Uhlig, Nadja
(author)
-
Eberlein, Valentina
(author)
-
Conzelmann, Carina
(author)
-
Olari, Lia-Raluca
(author)
-
Rauch, Lena
(author)
-
Lawrenz, Jan
(author)
-
Weil, Tatjana
(author)
-
Müller, Janis A.
(author)
-
Cardoso, Mateus Borba
(author)
-
Gilg, Andrea
(author)
-
Larsson, Olivia
(author)
-
Höglund, Urban
(author)
-
Axberg Pålsson, Sandra,1991-Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut(Swepub:su)sapa8421
(author)
-
Tvilum, Anna Selch
(author)
-
Løvschall, Kaja Borup
(author)
-
Kristensen, Maria M.
(author)
-
Spetz, Anna-Lena,1947-Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut(Swepub:su)aspet
(author)
-
Hontonnou, Fortune
(author)
-
Galloux, Marie
(author)
-
Grunwald, Thomas
(author)
-
Zelikin, Alexander N.
(author)
-
Münch, Jan
(author)
-
Stockholms universitetInstitutionen för molekylär biovetenskap, Wenner-Grens institut
(creator_code:org_t)
Related titles
-
In:Advanced Science: Wiley9:202198-3844
Internet link
Find in a library
To the university's database
- By the author/editor
-
Groß, Rüdiger
-
Dias Loiola, Lív ...
-
Issmail, Leila
-
Uhlig, Nadja
-
Eberlein, Valent ...
-
Conzelmann, Cari ...
-
show more...
-
Olari, Lia-Raluc ...
-
Rauch, Lena
-
Lawrenz, Jan
-
Weil, Tatjana
-
Müller, Janis A.
-
Cardoso, Mateus ...
-
Gilg, Andrea
-
Larsson, Olivia
-
Höglund, Urban
-
Axberg Pålsson, ...
-
Tvilum, Anna Sel ...
-
Løvschall, Kaja ...
-
Kristensen, Mari ...
-
Spetz, Anna-Lena ...
-
Hontonnou, Fortu ...
-
Galloux, Marie
-
Grunwald, Thomas
-
Zelikin, Alexand ...
-
Münch, Jan
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Cell and Molecul ...
- Articles in the publication
-
Advanced Science
- By the university
-
Stockholm University