Search: onr:"swepub:oai:DiVA.org:su-206230" >
Long-term exposure ...
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Chen, JieStockholms universitet,Institutionen för naturgeografi
(author)
Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort : the ELAPSE project
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2022-02-16
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Springer Science and Business Media LLC,2022
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:su-206230
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-206230URI
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https://doi.org/10.1038/s41416-022-01735-4DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:148822804URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background: The evidence linking ambient air pollution to bladder cancer is limited and mixed.Methods: We assessed the associations of bladder cancer incidence with residential exposure to fine particles (PM2.5), nitrogen dioxide (NO2), black carbon (BC), warm season ozone (O3) and eight PM2.5 elemental components (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) in a pooled cohort (N = 302,493). Exposures were primarily assessed based on 2010 measurements and back-extrapolated to the baseline years. We applied Cox proportional hazard models adjusting for individual- and area-level potential confounders.Results: During an average of 18.2 years follow-up, 967 bladder cancer cases occurred. We observed a positive though statistically non-significant association between PM2.5 and bladder cancer incidence. Hazard Ratios (HR) were 1.09 (95% confidence interval (CI): 0.93–1.27) per 5 µg/m3 for 2010 exposure and 1.06 (95% CI: 0.99–1.14) for baseline exposure. Effect estimates for NO2, BC and O3 were close to unity. A positive association was observed with PM2.5 zinc (HR 1.08; 95% CI: 1.00–1.16 per 10 ng/m3).Conclusions: We found suggestive evidence of an association between long-term PM2.5 mass exposure and bladder cancer, strengthening the evidence from the few previous studies. The association with zinc in PM2.5 suggests the importance of industrial emissions.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Rodopoulou, Sophia
(author)
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Strak, Maciej
(author)
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de Hoogh, Kees
(author)
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Taj, TahirKarolinska Institutet
(author)
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Poulsen, Aslak Harbo
(author)
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Andersen, Zorana J.
(author)
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Bellander, Tom
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Brandt, Jørgen
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Zitt, Emanuel
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Fecht, Daniela
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Forastiere, Francesco
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Gulliver, John
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Hertel, Ole
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Hoffmann, Barbara
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Hvidtfeldt, Ulla Arthur
(author)
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Verschuren, W. M. Monique
(author)
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Jørgensen, Jeanette T.
(author)
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Katsouyanni, KleaKarolinska Institutet
(author)
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Ketzel, Matthias
(author)
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Lager, Anton C. J.Karolinska Institutet,Stockholms universitet,Institutet för social forskning (SOFI),Centrum för forskning om äldre och åldrande (ARC), (tills m KI)(Swepub:su)antla
(author)
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Leander, Karin
(author)
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Liu, Shuo
(author)
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Ljungman, PetterKarolinska Institutet
(author)
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Severi, Gianluca
(author)
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Boutron-Ruault, Marie-Christine
(author)
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Magnusson, Patrik K. E.
(author)
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Nagel, Gabriele
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Pershagen, GöranKarolinska Institutet
(author)
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Peters, Annette
(author)
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Rizzuto, DeboraStockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institutet, Sweden; Stockholm Gerontology Research Center, Sweden
(author)
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van der Schouw, Yvonne T.
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Samoli, Evangelia
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Sørensen, Mette
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Stafoggia, Massimo
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Tjønneland, Anne
(author)
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Weinmayr, Gudrun
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Wolf, Kathrin
(author)
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Brunekreef, Bert
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Raaschou-Nielsen, Ole
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Hoek, Gerard
(author)
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Stockholms universitetInstitutionen för naturgeografi
(creator_code:org_t)
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In:British Journal of Cancer: Springer Science and Business Media LLC126:10, s. 1499-15070007-09201532-1827
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Chen, Jie
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Rodopoulou, Soph ...
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Strak, Maciej
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de Hoogh, Kees
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Taj, Tahir
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Poulsen, Aslak H ...
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Andersen, Zorana ...
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Bellander, Tom
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Brandt, Jørgen
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Zitt, Emanuel
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Fecht, Daniela
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Forastiere, Fran ...
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Gulliver, John
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Hertel, Ole
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Hoffmann, Barbar ...
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Hvidtfeldt, Ulla ...
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Verschuren, W. M ...
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Jørgensen, Jeane ...
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Katsouyanni, Kle ...
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Ketzel, Matthias
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Lager, Anton C. ...
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Leander, Karin
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Liu, Shuo
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Ljungman, Petter
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Severi, Gianluca
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Boutron-Ruault, ...
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Magnusson, Patri ...
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Nagel, Gabriele
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Pershagen, Göran
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Peters, Annette
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Rizzuto, Debora
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van der Schouw, ...
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Samoli, Evangeli ...
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Sørensen, Mette
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Stafoggia, Massi ...
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Tjønneland, Anne
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Weinmayr, Gudrun
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Wolf, Kathrin
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Brunekreef, Bert
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Raaschou-Nielsen ...
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Hoek, Gerard
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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Stockholm University
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Karolinska Institutet