onr:"swepub:oai:DiVA.org:su-207047"
Search: onr:"swepub:oai:DiVA.org:su-207047" > Mono-N-Alkylation o...
- 1 of 1
- Previous record
- Next record
- To hitlist
Mono-N-Alkylation of Sulfonamides with Alcohols Catalyzed by Iridium N-Heterocyclic Carbene-Phosphine Complexes
- Li, Xingzhen (author)
-
- Peters, Bram B. C. (author)
- Stockholms universitet,Institutionen för organisk kemi
- Tan, Min (author)
- show more...
- He, Lei (author)
- Zhou, Taigang (author)
- show less...
- (creator_code:org_t)
- 2022-06-21
- 2022
- English.
- In: Asian Journal of Organic Chemistry. - : Wiley. - 2193-5807 .- 2193-5815. ; 11:7
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- A N-heterocyclic carbene-phosphine iridium complex is presented for the efficient and selective mono-N-alkylation of sulfonamides with alcohols based on a borrowing hydrogenation strategy. Herein, water is the only by-product and this methodology thus offers a more environmentally benign and interesting alternative to the use of traditional alkylating reagents. This facile protocol tolerates a large number of (hetero) aromatic and aliphatic sulfonamides as well as (hetero) aromatic and aliphatic alcohols to obtain the desired product is high isolated yield (up to 98%). The alkylation completely retards after the formation of the secondary sulfonamide and no over-alkylation was observed in all cases. The option to run the reaction under solvent-free conditions as well as the scalability of this borrowing hydrogenation are key features of this protocol.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Keyword
- Alcohols
- Borrowing hydrogenation
- Iridium catalysis
- N-alkylation
- Sulfonamides
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Asian Journal of Organic Chemistry (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Li, Xingzhen
- Peters, Bram B. ...
- Tan, Min
- He, Lei
- Yang, Jianping
- Andersson, Pher ...
- show more...
- Zhou, Taigang
- show less...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Chemical Science ...
- Articles in the publication
- Asian Journal of ...
- By the university
- Stockholm University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
