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The discovAIR proje...
The discovAIR project : a roadmap towards the Human Lung Cell Atlas
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- Luecken, Malte D. (author)
- Helmholtz Zentrum Munchen, Inst Computat Biol, German Res Ctr Environm Hlth, Neuherberg, Germany.
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Zaragosi, Laure-Emmanuelle (author)
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Madissoon, Elo (author)
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Sikkema, Lisa (author)
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- Firsova, Alexandra B. (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för molekylär biovetenskap, Wenner-Grens institut
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De Domenico, Elena (author)
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Kümmerle, Louis (author)
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Saglam, Adem (author)
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Berg, Marijn (author)
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Gay, Aurore C. A. (author)
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Schniering, Janine (author)
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Mayr, Christoph H. (author)
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- Abalo, Xesús M. (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för biokemi och biofysik
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- Larsson, Ludvig (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för biokemi och biofysik
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- Sountoulidis, Alexandros (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för molekylär biovetenskap, Wenner-Grens institut
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Teichmann, Sarah A. (author)
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Van Eunen, Karen (author)
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Koppelman, Gerard H. (author)
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Saeb-Parsy, Kourosh (author)
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Leroy, Sylvie (author)
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Powell, Pippa (author)
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Sarkans, Ugis (author)
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Timens, Wim (author)
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- Lundeberg, Joakim (author)
- KTH,Science for Life Laboratory, SciLifeLab,Genteknologi
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van den Berge, Maarten (author)
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- Nilsson, Mats (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för biokemi och biofysik
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Horváth, Peter (author)
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Denning, Jessica (author)
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Papatheodorou, Irene (author)
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Schultze, Joachim L. (author)
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Schiller, Herbert B. (author)
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Barbry, Pascal (author)
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Petoukhov, Ilya (author)
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Misharin, Alexander V. (author)
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Adcock, Ian M. (author)
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von Papen, Michael (author)
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Theis, Fabian J. (author)
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- Samakovlis, Christos (author)
- Stockholms universitet,Science for Life Laboratory (SciLifeLab),Institutionen för molekylär biovetenskap, Wenner-Grens institut
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Meyer, Kerstin B. (author)
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- Nawijn, Martijn C. (author)
- Univ Groningen, Univ Med Ctr Groningen, Dept Pathol & Med Biol, Groningen, Netherlands.;Univ Med Ctr Groningen, GRIAC Res Inst, Groningen, Netherlands.
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Helmholtz Zentrum Munchen, Inst Computat Biol, German Res Ctr Environm Hlth, Neuherberg, Germany Science for Life Laboratory (SciLifeLab) (creator_code:org_t)
- 2022-01-27
- 2022
- English.
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In: European Respiratory Journal. - : European Respiratory Society (ERS). - 0903-1936 .- 1399-3003. ; 60:2
- Related links:
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https://doi.org/10.1...
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https://erj.ersjourn...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- The Human Cell Atlas (HCA) consortium aims to establish an atlas of all organs in the healthy human body at single-cell resolution to increase our understanding of basic biological processes that govern development, physiology and anatomy, and to accelerate diagnosis and treatment of disease. The Lung Biological Network of the HCA aims to generate the Human Lung Cell Atlas as a reference for the cellular repertoire, molecular cell states and phenotypes, and cell-cell interactions that characterise normal lung homeostasis in healthy lung tissue. Such a reference atlas of the healthy human lung will facilitate mapping the changes in the cellular landscape in disease. The discovAIR project is one of six pilot actions for the HCA funded by the European Commission in the context of the H2020 framework programme. discovAIR aims to establish the first draft of an integrated Human Lung Cell Atlas, combining single-cell transcriptional and epigenetic profiling with spatially resolving techniques on matched tissue samples, as well as including a number of chronic and infectious diseases of the lung. The integrated Human Lung Cell Atlas will be available as a resource for the wider respiratory community, including basic and translational scientists, clinical medicine, and the private sector, as well as for patients with lung disease and the interested lay public. We anticipate that the Human Lung Cell Atlas will be the founding stone for a more detailed understanding of the pathogenesis of lung diseases, guiding the design of novel diagnostics and preventive or curative interventions.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
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- By the author/editor
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Luecken, Malte D ...
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Zaragosi, Laure- ...
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Madissoon, Elo
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Sikkema, Lisa
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Firsova, Alexand ...
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De Domenico, Ele ...
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show more...
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Kümmerle, Louis
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Saglam, Adem
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Berg, Marijn
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Gay, Aurore C. A ...
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Schniering, Jani ...
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Mayr, Christoph ...
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Abalo, Xesús M.
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Larsson, Ludvig
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Sountoulidis, Al ...
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Teichmann, Sarah ...
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Van Eunen, Karen
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Koppelman, Gerar ...
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Saeb-Parsy, Kour ...
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Leroy, Sylvie
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Powell, Pippa
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Sarkans, Ugis
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Timens, Wim
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Lundeberg, Joaki ...
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van den Berge, M ...
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Nilsson, Mats
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Horváth, Peter
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Denning, Jessica
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Papatheodorou, I ...
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Schultze, Joachi ...
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Schiller, Herber ...
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Barbry, Pascal
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Petoukhov, Ilya
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Misharin, Alexan ...
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Adcock, Ian M.
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von Papen, Micha ...
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Theis, Fabian J.
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Samakovlis, Chri ...
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Meyer, Kerstin B ...
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Nawijn, Martijn ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Cell and Molecul ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
- Articles in the publication
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European Respira ...
- By the university
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Stockholm University
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Royal Institute of Technology